{"id":"W2974666543","doi":"10.1515/cdbme-2019-0041","title":"Biodegradable magnetic microspheres for drug targeting, temperature controlled drug release, and hyperthermia","year":2019,"lang":"en","type":"article","venue":"Current Directions in Biomedical Engineering","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Magnetic hyperthermia; Magnetic nanoparticles; PLGA; Materials science; Hyperthermia; Nanoparticle; Targeted drug delivery; Drug; Camptothecin; Drug delivery; Nanotechnology; Chemistry; Chemical engineering; Organic chemistry; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004651655,0.0002602054,0.000444858,0.0001957749,0.0001239155,0.00002503812,0.0001506984,0.000195637,0.0002452974],"category_scores_gemma":[0.0002494201,0.000233697,0.0001009908,0.0003742185,0.00009992599,0.00009964555,0.00004964489,0.0007089739,0.00003992562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001017145,"about_ca_system_score_gemma":0.00004480025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001925499,"about_ca_topic_score_gemma":0.000006911882,"domain_scores_codex":[0.9984669,0.0001020687,0.0004405531,0.0003974983,0.000129,0.0004639893],"domain_scores_gemma":[0.9988627,0.0006418109,0.00007330161,0.0001438208,0.00005963015,0.0002187676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002043163,0.0022053,0.02455902,0.003056588,0.0005430788,0.00003990238,0.002500761,0.02456932,0.6282862,0.001075253,0.1552874,0.1558341],"study_design_scores_gemma":[0.006907301,0.0000504375,0.000252913,0.0002029683,0.00005428402,0.0000148352,0.000171569,0.09972931,0.003595338,0.00002796466,0.8886216,0.0003714811],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9291109,0.06121766,0.0002645049,0.0003740948,0.007009825,0.001533878,0.0001069805,0.0002483647,0.0001338145],"genre_scores_gemma":[0.992281,0.002118167,0.00128903,0.0001098431,0.0005173853,0.0005150021,0.00008663063,0.00006080115,0.003022111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7333342,"threshold_uncertainty_score":0.9529887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0191099098730804,"score_gpt":0.3330261214582657,"score_spread":0.3139162115851853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}