{"id":"W2974693007","doi":"10.1182/blood.v130.suppl_1.3135.3135","title":"Selinexor in Combination with Weekly Low Dose Bortezomib and Dexamethasone (SVd) Induces a High Response Rate with Durable Responses in Patients with Refractory Multiple Myeloma (MM)","year":2017,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Hôpital Maisonneuve-Rosemont; Vancouver General Hospital; CancerCare Manitoba; University of Toronto; Royal Victoria Hospital; Dalhousie University","funders":"","keywords":"Medicine; Tolerability; Bortezomib; Dexamethasone; Combination therapy; Internal medicine; Lenalidomide; Ixazomib; Oncology; Pharmacology; Refractory (planetary science); Multiple myeloma; Carfilzomib; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006268845,0.0004387947,0.0009689628,0.0002649733,0.0001478435,0.0004318208,0.0003108273,0.0002966489,0.001400824],"category_scores_gemma":[0.0003812705,0.0001981594,0.000456807,0.0002601118,0.0002540806,0.0002545786,0.0001987957,0.001152283,0.0003218751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003294265,"about_ca_system_score_gemma":0.0002805293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002732443,"about_ca_topic_score_gemma":0.001109074,"domain_scores_codex":[0.9997811,0.00009104585,0.00001685475,0.00004339296,0.00002948483,0.00003831073],"domain_scores_gemma":[0.9997525,0.00006311128,0.000065593,0.00002160488,0.00000940415,0.00008788855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1652415,0.03503701,0.03335132,0.0009164063,0.0009988777,0.0006256781,0.0004851882,0.004333326,0.2287271,0.0002750508,0.005605743,0.5244028],"study_design_scores_gemma":[0.07946058,0.6949983,0.1523822,0.00009008228,0.000570473,0.002278443,0.0001874063,0.00428756,0.05484087,0.0002486042,0.01060857,0.00004691332],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968442,0.00155492,0.0002783557,0.0001251797,0.00002972763,0.0001654761,0.0001734802,0.00007507814,0.0007536876],"genre_scores_gemma":[0.9973648,0.0005910441,0.000520952,0.0001420138,0.00004159459,0.00009172875,0.0004102146,0.00001013917,0.0008275199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001400824,"threshold_uncertainty_score":0.004686236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01748938309382799,"score_gpt":0.2700816504739628,"score_spread":0.2525922673801348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}