{"id":"W2974900478","doi":"10.1371/journal.pone.0222580","title":"Suppressive impact of metronomic chemotherapy using UFT and/or cyclophosphamide on mediators of breast cancer dissemination and invasion","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; University of Toronto; University of Waterloo; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Ontario Veterinary College, University of Guelph; Taiho Pharmaceutical","keywords":"In vivo; Cyclophosphamide; Chemotherapy; Cancer research; Metastasis; Medicine; Tegafur; Breast cancer; Matrigel; Metastatic breast cancer; Prodrug; Fluorouracil; Toxicity; Internal medicine; Cancer; Oncology; Pharmacology; Angiogenesis; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009501197,0.0002291088,0.0002481773,0.0001366663,0.00008389974,0.0001907902,0.00009829708,0.0001523227,0.001328567],"category_scores_gemma":[0.0001329192,0.00007354117,0.0001239679,0.0001086175,0.0001515425,0.00013758,0.0001040241,0.0002621408,0.0001023822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001273946,"about_ca_system_score_gemma":0.0001895986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005109627,"about_ca_topic_score_gemma":0.001013511,"domain_scores_codex":[0.9999207,0.00002211858,0.000005310039,0.00001086866,0.00001467584,0.00002629138],"domain_scores_gemma":[0.9999311,0.00002216894,0.00001177594,0.000008438297,0.000006271988,0.00002011848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006695601,0.0000736318,0.0002554949,0.0000329358,0.000005681591,0.00004602464,0.00001645246,0.00008873791,0.9959677,0.0000438068,0.0000397664,0.002760274],"study_design_scores_gemma":[0.00006420689,0.004307748,0.008983522,0.000007043773,0.00002913182,0.0002841063,0.00003331702,0.0005978891,0.9838156,0.00002392793,0.001849274,0.00000431801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972705,0.001419169,0.0002828836,0.00004330513,0.00001894188,0.00001809556,0.00009373099,0.00002081309,0.0008325694],"genre_scores_gemma":[0.9983565,0.0005341261,0.0002553195,0.00001592024,0.00001127799,0.00001689444,0.0001377194,0.000003992755,0.0006683001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001328567,"threshold_uncertainty_score":0.00444448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02221464531787889,"score_gpt":0.295016642745472,"score_spread":0.2728019974275931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}