{"id":"W2974949377","doi":"10.1039/c9sm01196j","title":"The first study on the impact of osmolytes in whole cells of high temperature-adapted microorganisms","year":2019,"lang":"en","type":"article","venue":"Soft Matter","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"Agence Nationale de la Recherche","keywords":"Hyperthermophile; Osmolyte; Microorganism; Chemistry; Extremophile; Proteome; Archaea; Biology; Biochemistry; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002603994,0.000104184,0.0001570095,0.00003139994,0.00005872801,0.0000372901,0.0002348107,0.00004468238,0.0009330662],"category_scores_gemma":[0.00001247841,0.0000469176,0.0000495844,0.0001208416,0.00005395857,0.00005156251,0.00004538385,0.0001025679,0.000426218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002030622,"about_ca_system_score_gemma":0.00001828167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004013072,"about_ca_topic_score_gemma":0.00007246424,"domain_scores_codex":[0.9992923,0.0000640264,0.0001986692,0.0001480997,0.0001525468,0.0001443386],"domain_scores_gemma":[0.9992675,0.0001905087,0.0001047517,0.0003891629,0.00003588889,0.00001220489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005958999,0.00005815267,0.02938476,0.000007677428,0.000009768097,4.424654e-7,0.0006846403,0.00007221956,0.9605699,0.00003050413,0.009113252,0.000009090842],"study_design_scores_gemma":[0.0002522825,0.0002371112,0.2704496,0.0000173159,0.000005247281,7.120498e-7,0.0003327604,0.000001757962,0.7282944,0.0002578363,0.00009893587,0.00005210112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984844,0.00001678245,0.000001210575,0.0006018417,0.0003152931,0.0003252902,0.00002231273,0.000007894804,0.0002250298],"genre_scores_gemma":[0.9992215,4.579648e-7,0.000008115348,0.0002365322,0.00003165288,0.000005676841,0.000001532393,0.00001136255,0.0004831604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2410648,"threshold_uncertainty_score":0.9999802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004999776720497061,"score_gpt":0.2120461172974482,"score_spread":0.2070463405769511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}