{"id":"W2974960379","doi":"10.1056/nejmoa1908681","title":"Nintedanib in Progressive Fibrosing Interstitial Lung Diseases","year":2019,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":2346,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"National Institute for Health and Care Research; Boehringer Ingelheim","keywords":"Nintedanib; Idiopathic pulmonary fibrosis; Medicine; Lung; Fibrosis; Tyrosine-kinase inhibitor; Interstitial lung disease; Pathology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001255073,0.0005050814,0.001050528,0.0002620299,0.0001604701,0.0002457886,0.0003213453,0.0003834184,0.002116032],"category_scores_gemma":[0.0006441566,0.0001419356,0.0006221881,0.0002205786,0.0003716355,0.0002017798,0.0001863567,0.0007835508,0.0002057554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000296009,"about_ca_system_score_gemma":0.0004552556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003454629,"about_ca_topic_score_gemma":0.0008763583,"domain_scores_codex":[0.9996821,0.0001649794,0.00003396631,0.0000392031,0.00004386805,0.00003598391],"domain_scores_gemma":[0.9995995,0.000143933,0.0000918922,0.00001733819,0.00002649943,0.0001209534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5212001,0.01133159,0.01695267,0.004012183,0.001809364,0.0006649696,0.0001632492,0.00282396,0.06090109,0.0004241816,0.002830947,0.3768857],"study_design_scores_gemma":[0.5789251,0.3318795,0.06417996,0.0002524399,0.001526848,0.001535465,0.0000613559,0.002408202,0.01008491,0.0004981794,0.008609414,0.00003855552],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9713393,0.02455264,0.0005098817,0.0004240507,0.0002183905,0.0005954889,0.0002583,0.0000728595,0.002029008],"genre_scores_gemma":[0.9910077,0.006033508,0.0007605024,0.000387316,0.000187121,0.0003414644,0.0003520299,0.000005509812,0.000924725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002116032,"threshold_uncertainty_score":0.007078826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006852513408504109,"score_gpt":0.2727589832707856,"score_spread":0.2659064698622815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}