{"id":"W2975857794","doi":"10.1126/sciadv.aav2045","title":"No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication","year":2019,"lang":"en","type":"article","venue":"Science Advances","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Cancer Institute; National Institutes of Health","keywords":"Human immunodeficiency virus (HIV); Antiretroviral therapy; Compartmentalization (fire protection); Virology; Replication (statistics); ANTIRETROVIRAL AGENTS; Medicine; Biology; Viral load","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007200118,0.0001433573,0.0002802008,0.0004083986,0.0003307157,0.0005021196,0.0003855707,0.0005654629,0.001781597],"category_scores_gemma":[0.001818912,0.0001581736,0.0001171667,0.0003464575,0.0006225387,0.0008556288,0.0001732487,0.0005856415,0.00026345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002257648,"about_ca_system_score_gemma":0.0001796571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000640664,"about_ca_topic_score_gemma":0.0009213252,"domain_scores_codex":[0.9996362,0.00009913243,0.00002689873,0.00007444436,0.0001061839,0.00005717316],"domain_scores_gemma":[0.9982596,0.0006494175,0.0004516319,0.0001968741,0.0003013853,0.0001410636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001634563,0.0001068797,0.3850714,0.000312754,0.0000605427,0.00195961,0.0007494804,0.0002036827,0.5654585,0.0004214423,0.0001873701,0.04383373],"study_design_scores_gemma":[0.00002973399,0.001692714,0.8838614,0.0001549957,0.000151898,0.01166593,0.001307331,0.001289271,0.09288377,0.0007604721,0.006170952,0.00003152737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878016,0.007371121,0.001787568,0.0002724641,0.00002809955,0.00002186785,0.0001470657,0.00002500084,0.002545207],"genre_scores_gemma":[0.997006,0.001026334,0.001141056,0.0001299974,0.00002917952,0.00001829518,0.0001074293,0.000006042681,0.0005355459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001781597,"threshold_uncertainty_score":0.005959988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03340255070376773,"score_gpt":0.3642038977015633,"score_spread":0.3308013469977956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}