{"id":"W2975857794","doi":"10.1126/sciadv.aav2045","title":"No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication","year":2019,"lang":"en","type":"article","venue":"Science Advances","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Cancer Institute; National Institutes of Health","keywords":"Human immunodeficiency virus (HIV); Antiretroviral therapy; Compartmentalization (fire protection); Virology; Replication (statistics); ANTIRETROVIRAL AGENTS; Medicine; Biology; Viral load","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003711105,0.00007462801,0.0001271482,0.0001861917,0.0001975648,0.00001857723,0.0002398635,0.00003098367,0.00005222865],"category_scores_gemma":[0.0001961276,0.00005946717,0.0000219859,0.0004840902,0.0002639826,0.0009011702,0.00002767622,0.00004279098,0.0001561347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001216269,"about_ca_system_score_gemma":0.0001118074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001870906,"about_ca_topic_score_gemma":0.00001689587,"domain_scores_codex":[0.9990925,0.00004710777,0.00022487,0.0003517361,0.00006722254,0.0002165302],"domain_scores_gemma":[0.9991846,0.000141935,0.0001577377,0.0003237029,0.0001763746,0.00001564855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002085302,0.0001254738,0.2253519,0.00003532956,0.000005297211,4.696791e-8,0.0001869849,0.00004283091,0.7632072,0.0007797959,0.00002752631,0.01002905],"study_design_scores_gemma":[0.001677248,0.0008668844,0.3997533,0.0001514121,0.000004141385,0.000003893962,0.0001441291,0.0001128636,0.5950401,0.0002518458,0.001890862,0.0001033554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956148,0.002132412,0.0005232061,0.0004521628,0.00009279211,0.0009507544,0.00002922146,0.00002578777,0.0001788319],"genre_scores_gemma":[0.9976239,0.0004552239,0.000553319,0.00001351301,0.000005860474,0.0001593205,0.0001626931,0.000004531738,0.001021588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1744013,"threshold_uncertainty_score":0.2425001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03340255070376773,"score_gpt":0.3642038977015633,"score_spread":0.3308013469977956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}