{"id":"W2975971368","doi":"10.1016/j.dadm.2019.08.004","title":"Using subjective cognitive decline to identify high global amyloid in community‐based samples: A cross‐cohort study","year":2019,"lang":"en","type":"article","venue":"Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Janssen Pharmaceuticals; National Institute on Aging; National Health and Medical Research Council; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital; Genentech; National Institutes of Health; IXICO; Fidelity Biosciences; H. Lundbeck A/S; Servier; Eisai; Centre d'Imagerie BioMédicale; Pfizer; Biogen; BioClinica; National Center for Research Resources; F. Hoffmann-La Roche; AbbVie; University of Southern California; Northern California Institute for Research and Education; Massachusetts General Hospital; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; Sanofi; Harvard NeuroDiscovery Center; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Apolipoprotein E; Logistic regression; Odds ratio; Medicine; Positron emission tomography; Odds; Cognitive decline; Cohort; Internal medicine; Cognition; Oncology; Psychiatry; Nuclear medicine; Dementia; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007025926,0.0007894235,0.0004373571,0.0009818086,0.0009221635,0.001347281,0.0006269714,0.0009416232,0.001190316],"category_scores_gemma":[0.007133641,0.0005132725,0.0008384794,0.000652753,0.0005685328,0.000680868,0.0008090313,0.0007118342,0.0002667832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000238836,"about_ca_system_score_gemma":0.0004489494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004644455,"about_ca_topic_score_gemma":0.006995443,"domain_scores_codex":[0.9978887,0.001025479,0.0002087582,0.0004703602,0.0002688042,0.0001378433],"domain_scores_gemma":[0.9960935,0.0008452367,0.001071804,0.0009072755,0.0005909246,0.0004914383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005338975,0.000162132,0.9975544,0.00001285306,0.0003647844,0.00003109708,0.0001239454,0.00002677476,0.0002287622,0.00002420236,0.00004863049,0.0008886517],"study_design_scores_gemma":[0.00008113553,0.0006557591,0.9983279,0.000008878544,0.0001935418,0.0001158225,0.0001231664,0.0001790722,0.0001250836,0.00004337905,0.0001395007,0.000006772914],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992183,0.0001318684,0.00025263,0.00001443725,0.000007973207,0.00004684961,0.0001382128,0.000002578503,0.0001871654],"genre_scores_gemma":[0.9992723,0.00005167185,0.0002656968,0.00003793634,0.00001011805,0.00004024788,0.0001963603,0.000001849902,0.0001238109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007025926,"threshold_uncertainty_score":0.03715712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07088047905260604,"score_gpt":0.4514295518348361,"score_spread":0.3805490727822301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}