{"id":"W2976221451","doi":"10.1093/cid/ciz939","title":"Viral Kinetics and Resistance Development in Children Treated with Neuraminidase Inhibitors: The Influenza Resistance Information Study (IRIS)","year":2019,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"National Institute of Allergy and Infectious Diseases; Horizon 2020 Framework Programme; National Institutes of Health; Department of Health and Social Care; Gilead Sciences; Sanofi; Coalition for Epidemic Preparedness Innovations; F. Hoffmann-La Roche; Roche; GlaxoSmithKline","keywords":"Neuraminidase; Virology; IRIS (biosensor); Resistance (ecology); Medicine; Microbiology; Biology; Virus; Computer science; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002084263,0.0004674365,0.0005596064,0.0007122097,0.0003287228,0.0006307614,0.0003186909,0.0004605963,0.0008997117],"category_scores_gemma":[0.003815208,0.0003817982,0.0006982949,0.001094193,0.0002857388,0.0005845774,0.0004400017,0.0007371057,0.0002784942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003268939,"about_ca_system_score_gemma":0.0003811427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002634978,"about_ca_topic_score_gemma":0.002612474,"domain_scores_codex":[0.9988789,0.0004625468,0.0001257735,0.0002036834,0.0001794728,0.0001496256],"domain_scores_gemma":[0.9963386,0.0007441163,0.002081212,0.0002509038,0.000234901,0.0003501884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003569689,0.00001916876,0.9986548,0.00001442529,0.00004964932,0.00003699645,0.00005125346,0.00002296761,0.0001492324,0.000005473405,0.00004214446,0.0005967799],"study_design_scores_gemma":[0.00001943982,0.0003755182,0.9985435,0.00001109045,0.00004577152,0.0004855627,0.0001112864,0.0001075983,0.00009248147,0.000005188362,0.0001987739,0.00000370729],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986662,0.0004490257,0.00009110526,0.00002072079,0.000003416041,0.00001203764,0.0006016721,0.000003635171,0.0001522072],"genre_scores_gemma":[0.9985751,0.0002361361,0.0002040659,0.00001891899,0.00001020035,0.00001588495,0.0008674483,0.000004551143,0.00006769105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002634978,"threshold_uncertainty_score":0.01102281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03181781344232591,"score_gpt":0.3572053759722416,"score_spread":0.3253875625299157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}