{"id":"W2976396569","doi":"10.1080/15476286.2019.1667214","title":"Neuronal-specific microexon splicing of <i>TAF1</i> mRNA is directly regulated by SRRM4/nSR100","year":2019,"lang":"en","type":"article","venue":"RNA Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Deutschen Konsortium für Translationale Krebsforschung; Deutsche Forschungsgemeinschaft; Universität Konstanz; Saks-Kavanaugh Foundation","keywords":"TAF1; Biology; RNA splicing; Gene knockdown; Alternative splicing; Messenger RNA; Cell biology; Transcription factor II D; Gene isoform; Molecular biology; Genetics; RNA; Gene expression; Gene; RNA polymerase; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001165643,0.0002837981,0.0002076383,0.0001778854,0.0001298657,0.0002766684,0.0002091892,0.0001928316,0.0009057222],"category_scores_gemma":[0.0001156735,0.0001855914,0.0003128219,0.00008305039,0.000284795,0.0001336179,0.0002177362,0.0003399009,0.0006227265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000385538,"about_ca_system_score_gemma":0.0001687203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007061532,"about_ca_topic_score_gemma":0.00155748,"domain_scores_codex":[0.9998592,0.00001523544,0.00001019064,0.00004919599,0.00003864576,0.000027527],"domain_scores_gemma":[0.9998935,0.00001541662,0.00004434199,0.00001439766,0.00001206337,0.00002025333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001637314,0.000002868738,0.0001481811,0.000006174307,0.000001478119,0.00002904577,0.000004599979,0.00001124762,0.9992969,0.00005319122,0.00001187671,0.0004181841],"study_design_scores_gemma":[0.000004780306,0.00004639853,0.009301588,0.000003086424,0.000005365311,0.0002378732,0.00002159383,0.0005175992,0.988346,0.00003915993,0.00147331,0.000003175676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902815,0.0008636942,0.006429707,0.00006826223,0.00002402472,0.00001281026,0.0002114745,0.0001629736,0.001945466],"genre_scores_gemma":[0.9921476,0.0004420375,0.00381167,0.000043863,0.000007397442,0.00002061043,0.0006883129,0.00006907267,0.002769385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009057222,"threshold_uncertainty_score":0.003029943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007821725435240949,"score_gpt":0.2448171265218001,"score_spread":0.2369954010865591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}