{"id":"W2976604562","doi":"10.1002/art.41125","title":"Mediating Role of Bone Marrow Lesions, Synovitis, Pain Sensitization, and Depressive Symptoms on Knee Pain Improvement Following Substantial Weight Loss","year":2019,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute on Aging","keywords":"Medicine; Synovitis; Sensitization; Knee pain; Bone marrow; Anesthesia; Internal medicine; Arthritis; Osteoarthritis; Pathology; Immunology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006661682,0.0002984384,0.0008629482,0.0002059126,0.0001368868,0.0000183082,0.00005329963,0.0002343041,0.0001689619],"category_scores_gemma":[0.0004313774,0.000296419,0.0001524843,0.0001496371,0.00009802812,0.0001223356,0.00006770231,0.0001765735,0.00003787128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004382918,"about_ca_system_score_gemma":0.00008453292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009230698,"about_ca_topic_score_gemma":0.0001486764,"domain_scores_codex":[0.9976655,0.0003296765,0.0006624107,0.0005263653,0.0003224046,0.0004936812],"domain_scores_gemma":[0.998289,0.0008031984,0.0002800573,0.0003497247,0.00009536242,0.0001826935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002278614,0.0002199005,0.4801435,0.0001596101,0.0001894529,0.0004290942,0.000577908,0.000002419377,0.1106305,0.007220702,0.00009618742,0.4001029],"study_design_scores_gemma":[0.1450549,0.05844155,0.03562253,0.02801431,0.001170738,0.008063538,0.005883515,0.005584395,0.6875726,0.01495315,0.005058671,0.004580127],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903879,0.007304317,0.0001406144,0.000467122,0.0004131712,0.000884684,0.00003033792,0.00006687733,0.0003049654],"genre_scores_gemma":[0.9975659,0.001268844,0.0003860058,0.000314249,0.00003709572,0.00006330667,0.0002113656,0.00005381143,0.0000994855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.576942,"threshold_uncertainty_score":0.9999488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002919809510704455,"score_gpt":0.2011909480562615,"score_spread":0.1982711385455571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}