{"id":"W2976645875","doi":"10.1016/j.jcjd.2019.09.003","title":"Mechanisms by Which Glucagon-Like-Peptide-1 Receptor Agonists and Sodium-Glucose Cotransporter-2 Inhibitors Reduce Cardiovascular Risk in Adults With Type 2 Diabetes Mellitus","year":2019,"lang":"en","type":"review","venue":"Canadian Journal of Diabetes","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Alberta Innovates - Health Solutions","keywords":"Medicine; Incretin; Type 2 Diabetes Mellitus; Diabetes mellitus; Adverse effect; Glucagon-like peptide 1 receptor; Type 2 diabetes; Internal medicine; Glucagon-like peptide-1; Cardiac fibrosis; Endocrinology; Pharmacology; Receptor; Bioinformatics; Cardiology; Fibrosis; Agonist","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005130287,0.000675555,0.002131693,0.001251353,0.0001493098,0.0006735926,0.0007939939,0.0007021784,0.003341811],"category_scores_gemma":[0.0007927683,0.0002411346,0.0008926581,0.001090196,0.0002277013,0.000427953,0.0003128251,0.001363112,0.0009463261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005143138,"about_ca_system_score_gemma":0.0009054814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004743367,"about_ca_topic_score_gemma":0.01190664,"domain_scores_codex":[0.9998405,0.00002861723,0.00003127196,0.00002087246,0.00005988235,0.00001893776],"domain_scores_gemma":[0.999724,0.0001357521,0.00005726489,0.000004486817,0.00005726134,0.00002121852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005789603,0.0001473817,0.0005003016,0.03925686,0.001245084,0.0001436985,0.0000420644,0.0003105211,0.001056114,0.001456615,0.03262264,0.9226398],"study_design_scores_gemma":[0.001251969,0.000841616,0.01183682,0.02415414,0.005571648,0.001419996,0.0001638852,0.0003631093,0.0007863367,0.002761285,0.9507497,0.00009943844],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001454499,0.999216,0.00003043649,0.0001388075,0.0001077162,0.00000373315,0.00002238923,0.000003795177,0.0003318126],"genre_scores_gemma":[0.0007945689,0.9986079,0.00009242564,0.0001722988,0.0001180609,0.000004870946,0.00002895505,6.923528e-7,0.0001802855],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004743367,"threshold_uncertainty_score":0.01117951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01114218631351409,"score_gpt":0.222069525246665,"score_spread":0.2109273389331509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}