{"id":"W2976658222","doi":"10.1101/784371","title":"Clickable methionine as a universal probe for labelling intracellular bacteria","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"Medical Research Council; National Institutes of Health; National Science and Technology Development Agency; Royal Society","keywords":"Obligate; Intracellular; Intracellular parasite; Bacteria; Biology; Pathogen; Cell biology; Biochemistry; Computational biology; Microbiology; Genetics; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001247857,0.000651406,0.0004163373,0.0005811097,0.0003096894,0.0003628641,0.0005097776,0.0008514224,0.001970245],"category_scores_gemma":[0.0007365741,0.0003117105,0.0003396861,0.0003188927,0.0006531264,0.0004281466,0.0006974656,0.001088743,0.0009255101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003591892,"about_ca_system_score_gemma":0.0003618468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003061389,"about_ca_topic_score_gemma":0.0005805389,"domain_scores_codex":[0.9993111,0.0001794632,0.00004731236,0.0001683298,0.0001841193,0.00010969],"domain_scores_gemma":[0.9995363,0.0001569783,0.00007686869,0.00008549518,0.00007028417,0.00007416582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000234207,0.000006425098,0.00004121389,0.00007595988,0.000004873392,0.00005444733,0.00002151996,0.00003320534,0.998,0.0003734182,0.00007999195,0.001285469],"study_design_scores_gemma":[0.000004801886,0.0000833389,0.0002043109,0.000008774619,0.000009741385,0.0001714371,0.000007392079,0.0002896856,0.9953798,0.00009926097,0.00373538,0.000006164585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6949013,0.007544031,0.2872294,0.0008437472,0.0003957159,0.0002616528,0.0006672976,0.001442559,0.006714229],"genre_scores_gemma":[0.7817283,0.003163891,0.2025587,0.0003733585,0.0000954822,0.0002437084,0.001280886,0.0003438889,0.01021178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001970245,"threshold_uncertainty_score":0.006599367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02505494933366185,"score_gpt":0.2737087692448721,"score_spread":0.2486538199112103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}