{"id":"W2976721221","doi":"10.1038/s41379-019-0374-x","title":"Malignant transformation of liver fatty acid binding protein-deficient hepatocellular adenomas: histopathologic spectrum of a rare phenomenon","year":2019,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Cholangiocarcinoma and Gallbladder Cancer Studies","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"Institut National de la Santé et de la Recherche Médicale","keywords":"Hepatocellular adenoma; Hepatocellular carcinoma; Fatty acid-binding protein; Pathology; Malignant transformation; Fatty liver; Adenoma; Atypia; Steatosis; Medicine; Nuclear atypia; Biology; Internal medicine; Immunohistochemistry; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000277668,0.0002187675,0.000770419,0.0002413685,0.00004587326,0.000003807724,0.0001315829,0.0001466814,0.00008975734],"category_scores_gemma":[0.00002087185,0.0001801028,0.0001979066,0.0001682997,0.0001388216,0.0000728438,0.00006639129,0.0001781293,0.00003677941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001269562,"about_ca_system_score_gemma":0.0000642264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002063629,"about_ca_topic_score_gemma":0.000007016649,"domain_scores_codex":[0.9984034,0.00008975454,0.0005297436,0.000378407,0.0002640646,0.0003346835],"domain_scores_gemma":[0.9991338,0.00001819729,0.0002699451,0.0004276941,0.00009414912,0.0000562377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003499142,0.00024449,0.04480047,0.003640261,0.00005218884,0.0002934274,0.01044791,0.00001580649,0.9390212,0.0005948465,0.000005972412,0.0005335663],"study_design_scores_gemma":[0.005266319,0.004418452,0.09801566,0.00168248,0.0005690334,0.0007659568,0.001889044,0.003173029,0.8825657,0.0009424965,0.0000942901,0.0006175415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870575,0.00570431,0.003721277,0.0002255433,0.000116842,0.001452696,0.00004163274,0.000042206,0.001637992],"genre_scores_gemma":[0.9988763,0.0001061053,0.0005291011,0.00005963542,0.00002647638,0.00007804224,0.0000343376,0.00002428822,0.0002656845],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05645544,"threshold_uncertainty_score":0.7344379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02175763410263052,"score_gpt":0.2257356712717178,"score_spread":0.2039780371690873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}