{"id":"W2976945409","doi":"10.2196/13433","title":"Objectively Monitoring Amyotrophic Lateral Sclerosis Patient Symptoms During Clinical Trials With Sensors: Observational Study","year":2019,"lang":"en","type":"article","venue":"JMIR mhealth and uhealth","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; King's College London; Motor Neurone Disease Association; National Institute for Health and Care Research; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research; Economic and Social Research Council; South London and Maudsley NHS Foundation Trust","keywords":"Observational study; Amyotrophic lateral sclerosis; Medicine; Clinical trial; Physical medicine and rehabilitation; Physical therapy; Disease; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006531256,0.0006285698,0.001487818,0.0006981093,0.0008116238,0.001208214,0.0004408579,0.0009655291,0.001434783],"category_scores_gemma":[0.01452323,0.0003558806,0.001237696,0.0009699442,0.0007737675,0.001184476,0.0006888512,0.0009731672,0.0004669725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005334889,"about_ca_system_score_gemma":0.0008924433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006909318,"about_ca_topic_score_gemma":0.0009362057,"domain_scores_codex":[0.9935955,0.003439063,0.00112506,0.0007053441,0.0008944051,0.0002405793],"domain_scores_gemma":[0.980079,0.006378054,0.009107429,0.00149528,0.001730707,0.001209458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03457893,0.009722579,0.9274127,0.0008529405,0.002321461,0.0003532011,0.001407463,0.0003346069,0.001934962,0.00007814066,0.0007242454,0.0202787],"study_design_scores_gemma":[0.005746946,0.1070349,0.8769572,0.0002176316,0.001959808,0.0008706708,0.001352831,0.001427504,0.001341201,0.000151392,0.002841913,0.00009789379],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979372,0.0007390388,0.0003285251,0.00003144463,0.00000951731,0.0003689755,0.0002558012,0.000006298987,0.0003232074],"genre_scores_gemma":[0.9979302,0.0002721304,0.0004460468,0.0001069206,0.00002885991,0.0005271616,0.0005355942,0.000003677158,0.0001492775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006531256,"threshold_uncertainty_score":0.03454101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3291745046114749,"score_gpt":0.4804788899793166,"score_spread":0.1513043853678417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}