{"id":"W2977077732","doi":"10.3390/antiox8100428","title":"Red-Osier Dogwood Extracts Prevent Inflammatory Responses in Caco-2 Cells and a Caco-2 BBe1/EA.hy926 Cell Co-Culture Model","year":2019,"lang":"en","type":"article","venue":"Antioxidants","topic":"Tannin, Tannase and Anticancer Activities","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; University of Manitoba","keywords":"Quercetin; VCAM-1; Proinflammatory cytokine; Tumor necrosis factor alpha; Chemistry; Caco-2; Pharmacology; Cell adhesion molecule; Biochemistry; Cytokine; ICAM-1; Inflammation; Molecular biology; Biology; Intracellular; Cell; Immunology; Antioxidant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002197325,0.0005585874,0.0005645084,0.0003854017,0.0001569255,0.0002968323,0.0002061984,0.0003561716,0.001192553],"category_scores_gemma":[0.0001028115,0.0002134439,0.0004617167,0.0002885748,0.0001653315,0.0002951281,0.0002525561,0.0009331729,0.0002477485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001431755,"about_ca_system_score_gemma":0.0001739079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008148359,"about_ca_topic_score_gemma":0.001772718,"domain_scores_codex":[0.9998083,0.00003683634,0.00001980444,0.00003705399,0.00005142822,0.00004674348],"domain_scores_gemma":[0.9998883,0.00001574189,0.0000397184,0.00001501502,0.00002054957,0.00002070419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005040938,0.0002706498,0.0002422732,0.0001568459,0.00001348896,0.0001222782,0.00003203114,0.00005853368,0.9969649,0.00006155256,0.0001171729,0.001456247],"study_design_scores_gemma":[0.00008491704,0.002932025,0.01036039,0.0000368439,0.0001083904,0.0005100521,0.000117045,0.001477839,0.9771032,0.00005246601,0.007200736,0.00001608802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856986,0.007255439,0.003874419,0.0003012646,0.0001744835,0.00007146251,0.0005481675,0.0001456257,0.001930434],"genre_scores_gemma":[0.9746972,0.00715455,0.008814673,0.0002611122,0.00006140301,0.0001651733,0.001396552,0.00003903381,0.007410336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001192553,"threshold_uncertainty_score":0.003989458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008832554163665003,"score_gpt":0.2442236531500217,"score_spread":0.2353910989863567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}