{"id":"W2977092852","doi":"10.1016/j.euroneuro.2019.08.127","title":"M27 AN INTEGRATIVE NETWORK-BASED ANALYSIS REVEALS GENE NETWORKS, BIOLOGICAL MECHANISMS, AND DRUG TARGETS IN ALZHEIMER'S DISEASE","year":2019,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Apelin; Diabetes mellitus; Medicine; Internal medicine; Pathogenesis; Endocrinology; Disease; Fibrosis; Gastroenterology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005218849,0.0005763911,0.0006670706,0.002324771,0.0004516054,0.0007882816,0.00045263,0.0002342669,0.00361584],"category_scores_gemma":[0.0007873229,0.0001589994,0.001323116,0.00193656,0.000258577,0.000401845,0.00059346,0.000354065,0.0003696709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006076851,"about_ca_system_score_gemma":0.0008664551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00536582,"about_ca_topic_score_gemma":0.007422363,"domain_scores_codex":[0.9997563,0.00006891599,0.00001246779,0.00008592699,0.00004002315,0.00003634497],"domain_scores_gemma":[0.9997603,0.00009815933,0.00005041946,0.00002436025,0.00003476036,0.00003191813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.006107288,0.0007419937,0.2679242,0.00290873,0.009141129,0.001666972,0.0008636813,0.1079965,0.238033,0.01917881,0.01433986,0.3310978],"study_design_scores_gemma":[0.0002413401,0.001028389,0.4985316,0.0002271191,0.005262259,0.001233725,0.0007685838,0.4216477,0.02220794,0.02573278,0.02300258,0.0001159968],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.922051,0.005177673,0.04872652,0.0007151555,0.00005746976,0.0001053071,0.01517854,0.001127557,0.006860718],"genre_scores_gemma":[0.9710966,0.001349454,0.01940861,0.00008782878,0.00002935615,0.0001012058,0.006385394,0.00007435025,0.001467218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00536582,"threshold_uncertainty_score":0.01209617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02235701539118648,"score_gpt":0.3297746462936487,"score_spread":0.3074176309024623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}