{"id":"W2977364032","doi":"10.1093/annonc/mdz250.052","title":"Pembrolizumab in patients with MSI-H advanced endometrial cancer from the KEYNOTE-158 study","year":2019,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Pembrolizumab; Endometrial cancer; Oncology; Internal medicine; Gynecology; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001219144,0.0005665119,0.001341091,0.0002390517,0.0002726738,0.0007378285,0.0004735669,0.0005696667,0.002660789],"category_scores_gemma":[0.00187234,0.0003350929,0.001466846,0.0005207828,0.0002115886,0.0007023648,0.000565791,0.001400733,0.0003536024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004607673,"about_ca_system_score_gemma":0.0006066068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001333632,"about_ca_topic_score_gemma":0.002916211,"domain_scores_codex":[0.9995533,0.0001570021,0.00004382911,0.00009628196,0.00005677976,0.00009275882],"domain_scores_gemma":[0.9994681,0.000132195,0.0001399636,0.00006351781,0.00005569533,0.000140567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4604161,0.002424803,0.3192601,0.006712393,0.03169642,0.001477198,0.0004618235,0.001868113,0.01542701,0.00145187,0.02440136,0.1344029],"study_design_scores_gemma":[0.1353998,0.02273165,0.7617962,0.00133387,0.03786658,0.00171826,0.0006360599,0.001060371,0.001845324,0.00144636,0.03402964,0.0001358092],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9729855,0.01761393,0.0002437276,0.000820747,0.0001744837,0.0002339553,0.004783174,0.00001175119,0.003132779],"genre_scores_gemma":[0.9865413,0.004901961,0.0002256437,0.0009175631,0.0002514718,0.0002116127,0.005892965,0.000008430655,0.001049049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002660789,"threshold_uncertainty_score":0.008901179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04717057556773591,"score_gpt":0.3728451624856562,"score_spread":0.3256745869179203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}