{"id":"W2977365200","doi":"10.1093/annonc/mdz255","title":"Adjuvant nivolumab (NIVO) versus ipilimumab (IPI) in resected stage III/IV melanoma: 3-year efficacy and biomarker results from the phase III CheckMate 238 trial","year":2019,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Nivolumab; Ipilimumab; Adjuvant; Oncology; Internal medicine; Stage (stratigraphy); Melanoma; Biomarker; Immunotherapy; Cancer; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001150563,0.0008484562,0.001357662,0.0001960963,0.0002173585,0.0009645637,0.0005272764,0.0006674624,0.001719406],"category_scores_gemma":[0.001040928,0.0002583274,0.001556114,0.0002074046,0.0005040317,0.0007380237,0.0003081661,0.002036249,0.0004320123],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007843355,"about_ca_system_score_gemma":0.0006604626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008506054,"about_ca_topic_score_gemma":0.002227387,"domain_scores_codex":[0.9997537,0.0001121297,0.00001056881,0.0000530961,0.0000237045,0.00004679587],"domain_scores_gemma":[0.9994735,0.0001495521,0.0001313539,0.00005112045,0.0000245667,0.0001699333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.838971,0.007620732,0.01248813,0.0009984392,0.003654439,0.0001187649,0.0001407729,0.00308483,0.010978,0.0002639733,0.003733029,0.1179479],"study_design_scores_gemma":[0.6680239,0.239646,0.06841233,0.0002600697,0.006219432,0.000395821,0.00019935,0.004657544,0.004934086,0.001118292,0.006049221,0.00008389338],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994672,0.003067673,0.0001542611,0.0003029647,0.0001121388,0.0001444492,0.0005492426,0.00003816523,0.0009590589],"genre_scores_gemma":[0.99357,0.001755997,0.0004845568,0.0005813449,0.0001282774,0.0002386011,0.001486601,0.00002028262,0.001734333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001719406,"threshold_uncertainty_score":0.006084859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09707293265296456,"score_gpt":0.3960347247990392,"score_spread":0.2989617921460746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}