{"id":"W2977375633","doi":"10.14309/00000434-201310001-01721","title":"Early and Sustained Remission after Treatment with Subcutaneously Administered Golimumab Is Associated with Normalized Health-Related Quality of Life in Patients with Moderate to Severe Ulcerative Colitis: Post-hoc Analysis from PURSUIT Induction and Maintenance Trials","year":2013,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Medicine; Golimumab; Ulcerative colitis; Quality of life (healthcare); Internal medicine; Placebo; Post-hoc analysis; Randomized controlled trial; Randomization; Clinical trial; Physical therapy; Gastroenterology; Disease; Adalimumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009813579,0.0009557405,0.004037596,0.0004249063,0.0002990538,0.001288288,0.0007217306,0.0009755014,0.003153462],"category_scores_gemma":[0.006978634,0.0003792566,0.00608754,0.0005742928,0.000838463,0.001142504,0.0007327876,0.001789036,0.0002439733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003905832,"about_ca_system_score_gemma":0.0006264721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002659228,"about_ca_topic_score_gemma":0.0005310286,"domain_scores_codex":[0.9957272,0.002966751,0.0004335557,0.0003917593,0.0002556518,0.0002250446],"domain_scores_gemma":[0.9893065,0.006467763,0.002296716,0.0007913307,0.0003710495,0.0007667317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9666044,0.0006867477,0.005809675,0.0008880601,0.01100123,0.00003354474,0.00004272423,0.0002652114,0.001125295,0.00003247397,0.0002817399,0.01322891],"study_design_scores_gemma":[0.6419715,0.2194274,0.09311754,0.000314872,0.03985371,0.0002068113,0.0001151138,0.001755821,0.00123915,0.0003280075,0.001604437,0.00006573382],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9774336,0.01884079,0.000636811,0.0003773256,0.0001940156,0.0006797605,0.0008299045,0.00005165184,0.0009561293],"genre_scores_gemma":[0.9952266,0.002343337,0.0005020166,0.0002312912,0.0002080397,0.0003752925,0.0007779557,0.00001054222,0.0003248789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009813579,"threshold_uncertainty_score":0.05189979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008635153960372543,"score_gpt":0.2432969628432915,"score_spread":0.2346618088829189,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}