{"id":"W2977404659","doi":"10.4049/jimmunol.1801200","title":"Peroxisome Proliferator–Activated Receptor-δ Acts within Peripheral Myeloid Cells to Limit Th Cell Priming during Experimental Autoimmune Encephalomyelitis","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; St. Michael's Hospital; Toronto General Hospital; Women's College Hospital; University of Toronto","funders":"","keywords":"Experimental autoimmune encephalomyelitis; Myelin oligodendrocyte glycoprotein; CD11c; Adoptive cell transfer; Biology; Dendritic cell; Immunology; Inflammation; Receptor; Priming (agriculture); Peroxisome proliferator-activated receptor; T cell; Cell biology; Immune system; Phenotype; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003092086,0.0003510303,0.0003804762,0.0003909617,0.0002107379,0.0003318897,0.0002113878,0.0004122957,0.001152511],"category_scores_gemma":[0.0001802532,0.0001623073,0.0002515614,0.0001450033,0.0003934302,0.0002969438,0.0002689073,0.001270545,0.0006285258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000271703,"about_ca_system_score_gemma":0.0002390829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002641537,"about_ca_topic_score_gemma":0.0005083992,"domain_scores_codex":[0.9996736,0.00005740959,0.00004252203,0.00006875997,0.00006729525,0.00009035156],"domain_scores_gemma":[0.9997653,0.00002427565,0.00006466886,0.00003740106,0.00002974076,0.00007852337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002929094,0.00003649436,0.0002093221,0.00003963564,0.000001952602,0.00003354856,0.00001346599,0.00003011237,0.9983006,0.00004332164,0.00002796503,0.0009708173],"study_design_scores_gemma":[0.00009852809,0.00103079,0.007315212,0.00003407343,0.00002492449,0.0003322558,0.00009097163,0.0005677857,0.9880409,0.0001068857,0.002350458,0.000007260693],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922565,0.002371691,0.003173849,0.0002274371,0.00007285566,0.00007436179,0.0003341282,0.0001421911,0.001346957],"genre_scores_gemma":[0.9932621,0.0009846211,0.002936483,0.0001498075,0.00004547207,0.000100988,0.0002371562,0.0000335471,0.002249812],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001152511,"threshold_uncertainty_score":0.003855526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007602503835949816,"score_gpt":0.2121068546418128,"score_spread":0.204504350805863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}