{"id":"W2977570602","doi":"10.21769/bioprotoc.3075","title":"Ex vivo Culture and Lentiviral Transduction of Benign Prostatic Hyperplasia (BPH) Samples","year":2018,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Medical Research Council; Prostate Cancer UK; Wellcome Trust","keywords":"Ex vivo; Prostate; Transduction (biophysics); Biology; Cell culture; Cancer research; Stroma; Immunohistochemistry; Hyperplasia; Cell growth; In vivo; Viral vector; Cell biology; Pathology; Molecular biology; Gene; Immunology; Medicine; Recombinant DNA; Cancer; Genetics; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004977104,0.0002833234,0.00015824,0.000448468,0.0003377298,0.0004108948,0.0002703026,0.0003643496,0.003890969],"category_scores_gemma":[0.000139368,0.000223411,0.0002672493,0.0002506992,0.0002018746,0.0002083951,0.0002756142,0.0007930854,0.001777157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001840066,"about_ca_system_score_gemma":0.0004035385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006809625,"about_ca_topic_score_gemma":0.002515216,"domain_scores_codex":[0.9996783,0.00004875444,0.00002928838,0.00005446747,0.0001453588,0.00004379231],"domain_scores_gemma":[0.9999253,0.00001081951,0.00001233513,0.0000187535,0.00001427978,0.00001852876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008566902,0.00008494942,0.0006371851,0.0001170871,0.00001507941,0.0001718582,0.00005110143,0.00009539205,0.9889367,0.0006265444,0.0006872473,0.008491103],"study_design_scores_gemma":[0.0000312011,0.0003615233,0.005295898,0.00003265684,0.00004299076,0.001490759,0.00004090526,0.001332309,0.9526974,0.0001769739,0.03848675,0.00001067177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.7565842,0.01400554,0.164324,0.0009243546,0.001048687,0.002192922,0.01172599,0.001429369,0.04776486],"genre_scores_gemma":[0.8382808,0.00735416,0.08777519,0.0006075364,0.0001636558,0.001543603,0.01248728,0.0002354772,0.05155234],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.003890969,"threshold_uncertainty_score":0.01301658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04096952209950157,"score_gpt":0.3642650076793495,"score_spread":0.3232954855798479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}