{"id":"W2977710785","doi":"10.1158/0008-5472.can-19-1982","title":"MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"National Cancer Institute; National Institutes of Health; National Research Foundation of Korea; Ulsan National Institute of Science and Technology","keywords":"Cancer; Programmed cell death; Cancer research; Apoptosis; Biology; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002220167,0.00008872413,0.0002295758,0.0002081939,0.00002841619,0.000008285978,0.0001236438,0.00009378327,0.008122135],"category_scores_gemma":[0.000009576572,0.00007412954,0.00006715038,0.0004065651,0.00006433955,0.00006183369,0.00002855753,0.0002788818,0.00007499021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002407295,"about_ca_system_score_gemma":0.0006607893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001272518,"about_ca_topic_score_gemma":0.00004148431,"domain_scores_codex":[0.9985748,0.00009433303,0.000190127,0.0002551302,0.0005633114,0.0003222922],"domain_scores_gemma":[0.9992562,0.00006401634,0.00004387131,0.0003408817,0.0002041336,0.00009088014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001765133,0.0002526697,0.1056494,0.0003160916,0.00007369994,0.000008702827,0.001337609,0.00008537853,0.8834768,0.0003066424,0.002996689,0.003731242],"study_design_scores_gemma":[0.005046577,0.0004081268,0.1727058,0.0003584873,0.00002532899,9.971567e-7,0.0001614296,0.0008910813,0.8041747,0.002680159,0.01340454,0.0001427972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882822,0.007082875,0.00001416891,0.0006954542,0.000221513,0.0007775318,0.00002429325,0.00001152694,0.002890461],"genre_scores_gemma":[0.9909062,0.0008861984,0.00008048458,0.0002991566,0.0002741648,0.0001714707,0.000008955903,0.00002448824,0.007348839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07930208,"threshold_uncertainty_score":0.9927846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07206351326378002,"score_gpt":0.4225775402187747,"score_spread":0.3505140269549947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}