{"id":"W2977758416","doi":"10.1097/01.hs9.0000564720.36943.22","title":"S1618 TISAGENLECLEUCEL APPEARS EFFECTIVE AND SAFE IN PEDIATRIC AND YOUNG ADULT PATIENTS WITH RELAPSED/REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA WITH HIGH‐RISK CYTOGENETIC ABNORMALITIES","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Oncology; Internal medicine; Clinical endpoint; Gastroenterology; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002674492,0.0003348859,0.001001905,0.0002384614,0.0001042912,0.0003673988,0.0003141117,0.0004701862,0.004682467],"category_scores_gemma":[0.0004331357,0.0001172733,0.0004539663,0.0003516529,0.0002230654,0.0003445791,0.0001982985,0.0006876886,0.0006569739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003238231,"about_ca_system_score_gemma":0.0006282404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003922244,"about_ca_topic_score_gemma":0.001270642,"domain_scores_codex":[0.9998437,0.00007549259,0.00001294461,0.00002198179,0.00001885535,0.00002698459],"domain_scores_gemma":[0.999718,0.00004486887,0.00009136287,0.00001842581,0.00001475146,0.0001125359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2161195,0.01151163,0.02897326,0.001936939,0.001553555,0.00153893,0.0002826979,0.003212565,0.04476912,0.0008573721,0.01216946,0.677075],"study_design_scores_gemma":[0.2774373,0.4163899,0.189477,0.0005274823,0.001485778,0.008582087,0.000339915,0.005882407,0.02019287,0.001326443,0.07824595,0.0001129849],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866183,0.006465808,0.000690198,0.0004200804,0.00007230116,0.0003753495,0.001448053,0.000247126,0.003662768],"genre_scores_gemma":[0.9927154,0.001995046,0.0008425234,0.0004932446,0.00007666858,0.0002560228,0.001925203,0.00003069136,0.001665164],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004682467,"threshold_uncertainty_score":0.01566446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003459220271176016,"score_gpt":0.2095456919989019,"score_spread":0.2060864717277259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}