{"id":"W2977856690","doi":"10.3389/fimmu.2019.02307","title":"Bacille Calmette-Guérin Vaccine Strain Modulates the Ontogeny of Both Mycobacterial-Specific and Heterologous T Cell Immunity to Vaccination in Infants","year":2019,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Ottawa Hospital; University of Ottawa","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Allergy and Infectious Diseases; South African Medical Research Council; Medical Research Council; National Institutes of Health; Canadian Institutes of Health Research; Office of Extramural Research, National Institutes of Health; International Development Research Centre","keywords":"Heterologous; Vaccination; Immunity; Strain (injury); Biology; Immunology; Immune system; Ontogeny; BCG vaccine; Virology; Medicine; Microbiology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001871814,0.0002041327,0.0001571324,0.0003370196,0.000146217,0.0002781086,0.0001260327,0.0002236903,0.0006594182],"category_scores_gemma":[0.0005720317,0.0001924345,0.0001330881,0.0001383605,0.0001754168,0.0001756198,0.0002004727,0.0003091578,0.000165543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001798341,"about_ca_system_score_gemma":0.0001709429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001034431,"about_ca_topic_score_gemma":0.0009840679,"domain_scores_codex":[0.999897,0.0000248605,0.000006516198,0.00001865033,0.00001575274,0.00003716788],"domain_scores_gemma":[0.999843,0.00003591688,0.00005361929,0.00001016582,0.00001727695,0.00004003204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001973404,0.0002738211,0.3141646,0.00009637776,0.00002779396,0.00110074,0.000967661,0.0002080081,0.6670339,0.0001954693,0.0001147626,0.01384339],"study_design_scores_gemma":[0.0000100529,0.001073603,0.973613,0.00002030867,0.00001916112,0.001121975,0.0003365836,0.0001891865,0.02303149,0.00004742694,0.0005322617,0.000004921569],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999673,0.0001007094,0.00003001605,0.000004808947,0.00000123936,0.000003975466,0.00002393305,0.000001403078,0.0001608603],"genre_scores_gemma":[0.9990523,0.0002606992,0.0001057882,0.00001091501,0.000002774039,0.00001189562,0.00009679941,0.000002039382,0.0004567127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001034431,"threshold_uncertainty_score":0.002205908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006473989691528959,"score_gpt":0.2147494283942464,"score_spread":0.2082754387027174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}