{"id":"W2977954489","doi":"10.1016/j.oraloncology.2019.09.011","title":"Leading edge or tumor core: Intratumor cancer stem cell niches in oral cavity squamous cell carcinoma and their association with stem cell function","year":2019,"lang":"en","type":"article","venue":"Oral Oncology","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"National Center for Advancing Translational Sciences; National Institute of Dental and Craniofacial Research; National Institute on Deafness and Other Communication Disorders; National Institutes of Health; National Cancer Institute; Cancer Center, University of Colorado; Grant Foundation","keywords":"Cancer stem cell; Cell sorting; Stem cell; Cancer research; Cancer; Cell; Pathology; Stem cell marker; Biology; Cluster of differentiation; Chemistry; Cell biology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002479122,0.000153323,0.0002553181,0.0008545716,0.0003039423,0.0008331719,0.0002270864,0.0003638822,0.002487199],"category_scores_gemma":[0.0003615215,0.0001359257,0.0001444239,0.000434807,0.00032807,0.0006858475,0.0003782274,0.0003342528,0.0003611173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002541365,"about_ca_system_score_gemma":0.0003648322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007225244,"about_ca_topic_score_gemma":0.001083952,"domain_scores_codex":[0.9998856,0.00001326394,0.000007505207,0.00001845511,0.00003567565,0.00003954689],"domain_scores_gemma":[0.9997928,0.00004606295,0.0000443497,0.00001378408,0.00003078326,0.00007230144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004078542,0.0002836578,0.09483387,0.0002742266,0.00004904721,0.001108743,0.001015499,0.0003244238,0.8400699,0.004449477,0.0005202664,0.05299233],"study_design_scores_gemma":[0.00009976196,0.001721331,0.5630895,0.00008805684,0.0002172047,0.005933594,0.004958264,0.007707828,0.3967914,0.005468606,0.01387183,0.00005257121],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951762,0.002767591,0.0006264303,0.00004919497,0.000009435332,0.00001084601,0.0001043883,0.00002609916,0.001229821],"genre_scores_gemma":[0.9983616,0.0004209416,0.0003411322,0.00001199079,0.000006773911,0.000006819056,0.00006634412,0.000005203619,0.0007790217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002487199,"threshold_uncertainty_score":0.00832057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03029287814580267,"score_gpt":0.2755541159463821,"score_spread":0.2452612378005795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}