{"id":"W2978088979","doi":"10.1016/j.celrep.2019.08.094","title":"The Pseudomonas aeruginosa T6SS Delivers a Periplasmic Toxin that Disrupts Bacterial Cell Morphology","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"H2020 Marie Skłodowska-Curie Actions; Center for Molecular Biosciences, University of Innsbruck; Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Medical Research Council; Centre National de la Recherche Scientifique; Université Paris Diderot; Imperial College London; Horizon 2020 Framework Programme; Wellcome Trust","keywords":"Type VI secretion system; Periplasmic space; Effector; Pseudomonas aeruginosa; Secretion; Biology; Cell biology; Virulence; Microbiology; Bacteria; Bacterial cell structure; Biochemistry; Escherichia coli; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008484073,0.0003061862,0.0001491381,0.0001265864,0.000185151,0.0003195361,0.0001562385,0.0003571557,0.0009066011],"category_scores_gemma":[0.00009162758,0.00007451777,0.0002213069,0.000120101,0.0002403189,0.0001682069,0.0002132046,0.0005812886,0.0004449821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003079059,"about_ca_system_score_gemma":0.0002106919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001254345,"about_ca_topic_score_gemma":0.00129293,"domain_scores_codex":[0.9998648,0.00001911791,0.000009011603,0.00002018741,0.00005391052,0.00003296169],"domain_scores_gemma":[0.9999349,0.00001406185,0.00001452121,0.00001122752,0.00000899296,0.00001629748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001373744,0.000006537913,0.00005475788,0.000005476646,7.953391e-7,0.00003792956,0.000005796154,0.00001264532,0.9995418,0.00004876331,0.00001123694,0.0002605654],"study_design_scores_gemma":[0.000002414318,0.00009130368,0.001057018,0.000001397844,0.000002360886,0.0002128656,0.00001755118,0.000240273,0.9975937,0.00003501468,0.0007442178,0.000001907009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859866,0.000869068,0.008761052,0.0002985972,0.0000499283,0.00003244698,0.0003629361,0.0001420525,0.003497276],"genre_scores_gemma":[0.9920152,0.0005073819,0.002912719,0.00007692318,0.000008195637,0.00001565156,0.0002839412,0.00002350349,0.004156519],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001254345,"threshold_uncertainty_score":0.003032863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007927629248451308,"score_gpt":0.2312917977400045,"score_spread":0.2233641684915532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}