{"id":"W2978088979","doi":"10.1016/j.celrep.2019.08.094","title":"The Pseudomonas aeruginosa T6SS Delivers a Periplasmic Toxin that Disrupts Bacterial Cell Morphology","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"H2020 Marie Skłodowska-Curie Actions; Center for Molecular Biosciences, University of Innsbruck; Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Medical Research Council; Centre National de la Recherche Scientifique; Université Paris Diderot; Imperial College London; Horizon 2020 Framework Programme; Wellcome Trust","keywords":"Type VI secretion system; Periplasmic space; Effector; Pseudomonas aeruginosa; Secretion; Biology; Cell biology; Virulence; Microbiology; Bacteria; Bacterial cell structure; Biochemistry; Escherichia coli; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003364478,0.0002619638,0.000243094,0.00003477798,0.0002298663,0.00008945354,0.0002781037,0.0001850099,0.0001768014],"category_scores_gemma":[0.00008049245,0.0001957368,0.0001680351,0.00006503149,0.0002127066,0.000008246898,0.0005011733,0.0001643225,0.0001138734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004360502,"about_ca_system_score_gemma":0.0001712653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004452685,"about_ca_topic_score_gemma":0.00004061186,"domain_scores_codex":[0.9980472,0.0001178001,0.0003132977,0.0006509494,0.0002597292,0.0006110719],"domain_scores_gemma":[0.9985842,0.00004438481,0.0002256532,0.0009092946,0.00009990769,0.0001365744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001680504,0.00005066384,0.01224039,0.00002793563,0.00004061992,0.0002633744,0.00006802144,0.00001073075,0.9795983,0.000002326349,0.007257566,0.0002720427],"study_design_scores_gemma":[0.0005335106,0.0002580594,0.007219704,0.000006809403,0.00001789857,0.0002290864,0.0002343908,0.000007441126,0.7597007,0.00001583073,0.2315166,0.0002600051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986989,0.0008010381,0.00001882621,0.0001328775,0.001438559,0.0004803991,0.00001338667,0.00002118364,0.01010469],"genre_scores_gemma":[0.9861311,0.0008698726,0.00009800772,0.00008773346,0.0002391413,0.00004920163,0.0001198003,0.00003729585,0.0123679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.224259,"threshold_uncertainty_score":0.7981914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007927629248451308,"score_gpt":0.2312917977400045,"score_spread":0.2233641684915532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}