{"id":"W2978193882","doi":"10.1002/brb3.1375","title":"Chronic nicotine exposure attenuates the effects of Δ<sup>9</sup>‐tetrahydrocannabinol on anxiety‐related behavior and social interaction in adult male and female rats","year":2019,"lang":"en","type":"article","venue":"Brain and Behavior","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University","funders":"Natural Sciences and Engineering Research Council of Canada; Wilfrid Laurier University","keywords":"Nicotine; Anxiogenic; Elevated plus maze; Delta-9-tetrahydrocannabinol; Anxiolytic; Pharmacology; Nicotinic agonist; Cannabinoid; Tetrahydrocannabinol; Cannabinoid receptor; Mecamylamine; Psychology; Medicine; Anxiety; Internal medicine; Receptor; Antagonist; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008419058,0.0005346016,0.0003498693,0.000328315,0.0001885595,0.0002694483,0.0002987361,0.0003631593,0.002381646],"category_scores_gemma":[0.0001665638,0.0002541942,0.0002825928,0.0001098912,0.0004266847,0.0002058073,0.000220368,0.0009249996,0.0005634844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003711228,"about_ca_system_score_gemma":0.0004195361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003623424,"about_ca_topic_score_gemma":0.009852405,"domain_scores_codex":[0.9998401,0.00001436272,0.00001250329,0.00002859311,0.00004717984,0.00005721657],"domain_scores_gemma":[0.9997401,0.0000183113,0.00008006894,0.00002721186,0.00002666017,0.0001075638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001392395,0.0002998147,0.0008852204,0.00003369507,0.00002104748,0.00008383308,0.00004457206,0.00002875838,0.9945036,0.00004509995,0.00005908635,0.002602872],"study_design_scores_gemma":[0.0001361748,0.007680002,0.1053769,0.00004767378,0.0001252221,0.000527046,0.0002941768,0.0008333789,0.8831612,0.00009796514,0.001691496,0.0000288148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984095,0.0004368679,0.0002062647,0.00006943012,0.00001662386,0.00001288036,0.0001817993,0.00003947767,0.0006271675],"genre_scores_gemma":[0.9943424,0.0009193072,0.000533027,0.00009894224,0.00001768122,0.00004589142,0.0003863679,0.00001583564,0.003640613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003623424,"threshold_uncertainty_score":0.007967412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008103587287656788,"score_gpt":0.274562277412673,"score_spread":0.2664586901250162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}