{"id":"W2978195289","doi":"10.14309/00000434-201210001-01665","title":"A Phase 3 Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Safety and Efficacy of Subcutaneous Golimumab Maintenance Therapy in Patients with Moderately to Severely Active Ulcerative Colitis: PURSUIT-Maintenance","year":2012,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Medicine; Discontinuation; Internal medicine; Clinical endpoint; Placebo; Ulcerative colitis; Population; Randomized controlled trial; Golimumab; Maintenance therapy; Clinical trial; Gastroenterology; Surgery; Chemotherapy; Etanercept; Rheumatoid arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001709832,0.0009529068,0.002351182,0.0002898901,0.0004111561,0.0006365299,0.0006948953,0.0012102,0.004596655],"category_scores_gemma":[0.001511321,0.0004784518,0.001179126,0.0003212938,0.0008831675,0.000688179,0.0003429439,0.00191466,0.0006400897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004749688,"about_ca_system_score_gemma":0.001166517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003980301,"about_ca_topic_score_gemma":0.0009787336,"domain_scores_codex":[0.9994537,0.0002880448,0.00004363875,0.00009301301,0.0000536559,0.00006803005],"domain_scores_gemma":[0.9988043,0.0002852784,0.0003501189,0.0001217514,0.00008613852,0.0003523983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9736785,0.008810295,0.001076232,0.0002975764,0.0003886801,0.0000273779,0.0000326376,0.0001400496,0.003815517,0.00003859588,0.0003869165,0.01130761],"study_design_scores_gemma":[0.9061729,0.09014059,0.002583883,0.00001506673,0.0001555206,0.00002501022,0.000009290107,0.0002505421,0.0003383604,0.00004629248,0.0002562891,0.000006282273],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917162,0.001639406,0.0005653077,0.0003152352,0.0001839877,0.003952497,0.0006930389,0.00009040069,0.0008440103],"genre_scores_gemma":[0.9891186,0.0008635398,0.001777844,0.000833791,0.0002659962,0.004991224,0.0009605844,0.00001437279,0.001174094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004596655,"threshold_uncertainty_score":0.01537734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009372323497448409,"score_gpt":0.2748104540680563,"score_spread":0.2654381305706078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}