{"id":"W2978344564","doi":"10.1093/annonc/mdz253.038","title":"Comprehensive results of a phase Ib study with a HER2/neu B-cell peptide vaccine administered with cisplatin and 5-fluorouracil or capecitabine chemotherapy show safety, immunogenicity and clinical response in patients with HER2/Neu overexpressing advanced gastric cancer","year":2019,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Capecitabine; Immunogenicity; Fluorouracil; Chemotherapy; Oncology; Cisplatin; Internal medicine; Peptide vaccine; Pharmacology; Immunology; Cancer; Immune system; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001969904,0.0009239801,0.001500375,0.0002455041,0.0004054616,0.0006045296,0.0003958943,0.0006565042,0.00102327],"category_scores_gemma":[0.0006092504,0.0002843083,0.0009084633,0.0003202277,0.0007240112,0.0006254078,0.0001893827,0.002061753,0.0003072931],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004864107,"about_ca_system_score_gemma":0.0009763099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009095238,"about_ca_topic_score_gemma":0.001477469,"domain_scores_codex":[0.9995739,0.0001955557,0.0000236064,0.00006009738,0.0000499768,0.00009695742],"domain_scores_gemma":[0.9994993,0.0001402336,0.00007001805,0.00007369338,0.00005509566,0.0001616755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1951136,0.1134914,0.02116161,0.001004989,0.00317574,0.0006470109,0.0009031952,0.00844283,0.4369993,0.0003732441,0.003585365,0.2151018],"study_design_scores_gemma":[0.07250195,0.8002533,0.04603929,0.00004191521,0.001470943,0.0007435036,0.0001461045,0.001494822,0.07244163,0.0002086529,0.004611377,0.00004646109],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956683,0.001337913,0.0008903267,0.0001858545,0.00005372769,0.0006234625,0.0003979903,0.00004774671,0.0007946903],"genre_scores_gemma":[0.9936712,0.001216613,0.001517451,0.0003747998,0.00005839819,0.0003902149,0.001696584,0.00003631854,0.001038373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001969904,"threshold_uncertainty_score":0.010418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05704754310577133,"score_gpt":0.415170055451637,"score_spread":0.3581225123458657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}