{"id":"W2978358810","doi":"10.1242/dev.180430","title":"<i>Lats1</i> and <i>Lats2</i> are required for the maintenance of multipotency in the Müllerian duct mesenchyme","year":2019,"lang":"en","type":"article","venue":"Development","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Ottawa; Université de Sherbrooke; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Biology; Hippo signaling pathway; Mesenchyme; Cell biology; Wnt signaling pathway; Mesoderm; Intermediate mesoderm; YAP1; Myofibroblast; Mesenchymal stem cell; Signal transduction; Genetics; Internal medicine; Embryonic stem cell; Embryo; Transcription factor; Embryogenesis; Fibrosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005032824,0.000117083,0.0001332395,0.00001956491,0.00006348718,0.00001255095,0.0002268083,0.00007278888,0.000004978053],"category_scores_gemma":[0.00008556563,0.00006831143,0.00004385109,0.00007055664,0.00005457526,0.000002660673,0.00006067533,0.00005908397,0.000004608628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008621104,"about_ca_system_score_gemma":0.00008244209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001791813,"about_ca_topic_score_gemma":0.00008168461,"domain_scores_codex":[0.9991705,0.00003924368,0.0002272649,0.0002437988,0.000114268,0.0002049053],"domain_scores_gemma":[0.9994707,0.00006653882,0.00009603328,0.0002865962,0.00005571208,0.00002443457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001530422,0.00007353691,0.009622207,0.00008635422,0.00006720935,0.000003389183,0.002334461,0.0000732706,0.977834,0.0001929445,0.0009640574,0.00859546],"study_design_scores_gemma":[0.00203407,0.0002385022,0.0436303,0.0001687886,0.0000189652,0.00002787742,0.002867724,0.0001708332,0.5097713,0.0001930435,0.440469,0.0004096024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966992,0.0009045558,0.000409842,0.0006197401,0.0001427855,0.0005823343,0.00001305469,0.000004334661,0.0006242057],"genre_scores_gemma":[0.9973096,0.0001155488,0.001269479,0.0005663771,0.00004602878,0.00008103132,0.00002345335,0.0000116618,0.0005768629],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4680628,"threshold_uncertainty_score":0.2785659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01342508481484802,"score_gpt":0.2269526869824667,"score_spread":0.2135276021676187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}