{"id":"W2978417493","doi":"10.1002/mgg3.859","title":"The CLN3 gene and protein: What we know","year":2019,"lang":"en","type":"review","venue":"Molecular Genetics & Genomic Medicine","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"Thornhill Medical (Canada)","funders":"Beyond Batten Disease Foundation","keywords":"Batten disease; Product (mathematics); Trademark; Disease; Data science; Computer science; Computational biology; Biology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008615527,0.0008248752,0.002435903,0.0003147837,0.0001835012,0.0001411722,0.0007182228,0.0005441332,0.0001401172],"category_scores_gemma":[0.0002742685,0.0005007652,0.0004025381,0.0004644807,0.0006754512,0.00003570947,0.0005608973,0.001031017,0.0003636711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002986925,"about_ca_system_score_gemma":0.0009312244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002298333,"about_ca_topic_score_gemma":0.00000533741,"domain_scores_codex":[0.9955428,0.0004095242,0.001048704,0.001042542,0.001055709,0.0009007542],"domain_scores_gemma":[0.9967692,0.0002145378,0.0003851818,0.001874337,0.0002284998,0.0005282208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003315239,0.0000356709,0.000001832972,0.0101901,0.0005489975,0.0003365376,0.0001324292,7.20886e-7,0.001712846,0.0000889626,0.0006889487,0.9862298],"study_design_scores_gemma":[0.001216861,0.0007035959,0.000005649017,0.01572982,0.001835981,0.0005939598,0.0001187949,0.00003767115,0.00009371622,0.0001079328,0.9791279,0.0004280763],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000418174,0.9895267,0.0002207321,0.00299044,0.0004737506,0.005762111,0.000009759857,0.0000403708,0.0005579235],"genre_scores_gemma":[0.00002691404,0.9909062,0.0003896746,0.0003811586,0.0005742979,0.0003233625,0.0001633376,0.0002581772,0.006976887],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9858018,"threshold_uncertainty_score":0.9997444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05139341970722693,"score_gpt":0.3536444176045216,"score_spread":0.3022509978972946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}