{"id":"W2978420588","doi":"10.1016/j.synbio.2019.09.001","title":"Brocaeloid D, a novel compound isolated from a wheat pathogenic fungus, Microdochium majus 99049","year":2019,"lang":"en","type":"article","venue":"Synthetic and Systems Biotechnology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"National Key Research and Development Program of China; Fundamental Research Funds for the Central Universities; Higher Education Discipline Innovation Project; State Key Laboratory of Bioreactor Engineering; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"HeLa; Fungus; Chemistry; Bioactive compound; IC50; Alkaloid; Stereochemistry; Active compound; Pathogenic fungus; Biology; Biochemistry; Botany; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004645557,0.0003508535,0.0002187028,0.000526386,0.0001830617,0.0001856938,0.0001677234,0.0002676474,0.0009836274],"category_scores_gemma":[0.00008035169,0.00009499984,0.000189812,0.0002131162,0.0001369277,0.0001552043,0.0001742756,0.0002861401,0.0002875652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001441526,"about_ca_system_score_gemma":0.0002746128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007416836,"about_ca_topic_score_gemma":0.00157611,"domain_scores_codex":[0.9999629,0.000003864784,0.000004415456,0.00001315818,0.000008582005,0.000007054547],"domain_scores_gemma":[0.9999697,0.000003600613,0.000006732677,0.000002720681,0.000005734245,0.00001154803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00019669,0.0000493843,0.0005975829,0.0003078212,0.00001190751,0.000442324,0.00002469607,0.0001638019,0.9834731,0.0001192422,0.0001492378,0.01446403],"study_design_scores_gemma":[0.0001684377,0.002245171,0.02136368,0.00006711419,0.00008187015,0.003035058,0.00007804003,0.0005639018,0.936268,0.0001621688,0.03592682,0.00003983417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9586034,0.01895007,0.006219111,0.0003345753,0.0001139953,0.0004062484,0.003242863,0.0001722229,0.01195757],"genre_scores_gemma":[0.978528,0.005385721,0.007795105,0.000279284,0.00003039524,0.00008458072,0.002958227,0.00001254,0.004926169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009836274,"threshold_uncertainty_score":0.003290534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00943475167793548,"score_gpt":0.2082663785825457,"score_spread":0.1988316269046102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}