{"id":"W2978420588","doi":"10.1016/j.synbio.2019.09.001","title":"Brocaeloid D, a novel compound isolated from a wheat pathogenic fungus, Microdochium majus 99049","year":2019,"lang":"en","type":"article","venue":"Synthetic and Systems Biotechnology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"National Key Research and Development Program of China; Fundamental Research Funds for the Central Universities; Higher Education Discipline Innovation Project; State Key Laboratory of Bioreactor Engineering; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"HeLa; Fungus; Chemistry; Bioactive compound; IC50; Alkaloid; Stereochemistry; Active compound; Pathogenic fungus; Biology; Biochemistry; Botany; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002175709,0.0003443848,0.0008420228,0.0002442066,0.000101613,0.00004973205,0.0002053994,0.0008809446,0.0001413124],"category_scores_gemma":[0.00007867415,0.000254001,0.000121272,0.0002664592,0.0002353419,0.00003600033,0.0001487405,0.0004884569,0.0003339507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006713349,"about_ca_system_score_gemma":0.00005596763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007824105,"about_ca_topic_score_gemma":0.00002991384,"domain_scores_codex":[0.9979706,0.00006005415,0.0004944011,0.0008281534,0.0001622611,0.0004844943],"domain_scores_gemma":[0.9987507,0.00009060555,0.0001628511,0.000786473,0.00008520814,0.0001241191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002332822,0.0001110495,0.0003961645,0.0001973198,0.0001625026,0.00003532802,0.00006778012,2.958647e-7,0.9932112,0.0005599284,0.0003401225,0.004685051],"study_design_scores_gemma":[0.006318952,0.001889743,0.002676211,0.00220911,0.0008625625,0.00930244,0.001827477,0.002523944,0.7029205,0.0002097441,0.2675796,0.001679771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824662,0.009830553,0.000259392,0.00455634,0.0009131207,0.001049612,0.0001849306,0.0002729582,0.0004669387],"genre_scores_gemma":[0.9960423,0.000403887,0.000474606,0.0002349127,0.0001588242,0.000003706727,0.000042983,0.00004350256,0.002595273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2902907,"threshold_uncertainty_score":0.9999912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00943475167793548,"score_gpt":0.2082663785825457,"score_spread":0.1988316269046102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}