{"id":"W2978617812","doi":"10.14309/00000434-201110002-01171","title":"Sustained Remission with No Dose Escalation after Re-induction with Certolizumab Pegol in Patients with Crohnʼs Disease Exacerbation: 1-Year Results from PRECiSE 4","year":2011,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Certolizumab pegol; Medicine; Maintenance therapy; Exacerbation; Placebo; Internal medicine; Gastroenterology; Surgery; Disease; Infliximab; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00182915,0.0005556695,0.001799946,0.000323716,0.0003295496,0.0007463472,0.0004587546,0.0006247831,0.001848711],"category_scores_gemma":[0.001525075,0.0002932081,0.001844355,0.0003823529,0.0003956451,0.0008592755,0.0007528569,0.001516229,0.0002964256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005213713,"about_ca_system_score_gemma":0.0007506906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004345323,"about_ca_topic_score_gemma":0.0009020744,"domain_scores_codex":[0.9993025,0.0002745639,0.0000679813,0.0001122706,0.00009449662,0.0001481311],"domain_scores_gemma":[0.9989408,0.0001762583,0.00037303,0.0001525616,0.00006368665,0.0002936859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8318892,0.01389043,0.02997123,0.0006048408,0.001663439,0.0002389302,0.0001956511,0.001736223,0.009244798,0.00008030698,0.0005934361,0.1098915],"study_design_scores_gemma":[0.1563259,0.6853381,0.1491352,0.00009251988,0.002068521,0.000337796,0.0001711169,0.001201075,0.003141331,0.0001710613,0.001973824,0.00004360047],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977958,0.001211073,0.0001443252,0.00005088272,0.00002086011,0.0002343824,0.000170357,0.00001108844,0.0003612012],"genre_scores_gemma":[0.9976559,0.0005110079,0.0002828199,0.0001079074,0.0000386469,0.0003280372,0.000587286,0.000003031034,0.0004854068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001848711,"threshold_uncertainty_score":0.009673595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004893454881791354,"score_gpt":0.1932255890100149,"score_spread":0.1883321341282235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}