{"id":"W2978650206","doi":"10.1093/annonc/mdz250.009","title":"Effect of response to last platinum-based chemotherapy in patients (pts) with platinum-sensitive, recurrent ovarian carcinoma in the phase III study ARIEL3 of rucaparib maintenance treatment","year":2019,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; Ottawa Hospital; University Health Network","funders":"","keywords":"Medicine; Oncology; Chemotherapy; Internal medicine; Ovarian cancer; Platinum; Ovarian carcinoma; Phases of clinical research; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00152942,0.0005523097,0.001935868,0.0002814077,0.0002819013,0.0007950338,0.0005905989,0.0009332018,0.001861333],"category_scores_gemma":[0.001691684,0.0002652457,0.001702531,0.0003218238,0.0004168091,0.0006182044,0.0003161721,0.002545098,0.0002857982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005553404,"about_ca_system_score_gemma":0.0008021994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001173818,"about_ca_topic_score_gemma":0.002786617,"domain_scores_codex":[0.9994653,0.0002728413,0.00003378601,0.00007624791,0.00004502683,0.0001068036],"domain_scores_gemma":[0.9989123,0.0003711021,0.0002036706,0.00008273141,0.00004016809,0.0003901057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8628973,0.008609371,0.04189942,0.0002729619,0.002537419,0.0001360628,0.0001234943,0.00180862,0.01040344,0.00007255313,0.001416425,0.06982304],"study_design_scores_gemma":[0.2061828,0.4895853,0.2906101,0.00006246264,0.002636603,0.0004543432,0.0001549478,0.003230637,0.004093122,0.000200826,0.00271432,0.00007451584],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974905,0.001290743,0.00006587233,0.0001499222,0.00004996061,0.0000719096,0.000359465,0.00001910313,0.0005025392],"genre_scores_gemma":[0.9974927,0.0004664347,0.0001259244,0.0002505905,0.00007658762,0.00007789332,0.0007827664,0.000009734712,0.0007173335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001935868,"threshold_uncertainty_score":0.00808847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03346109098614352,"score_gpt":0.3772049853250598,"score_spread":0.3437438943389163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}