{"id":"W2978837562","doi":"10.15698/mic2019.10.693","title":"Gut microbial metabolites in depression: understanding the biochemical mechanisms","year":2019,"lang":"en","type":"review","venue":"Microbial Cell","topic":"GABA and Rice Research","field":"Agricultural and Biological Sciences","cited_by":280,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Centre for Addiction and Mental Health; University Health Network; St. Michael's Hospital","funders":"Biotechnology and Biological Sciences Research Council; Government of Ontario; Medical Research Council; Ontario Brain Institute","keywords":"Gut flora; Gut–brain axis; Biology; Microbial metabolism; Function (biology); Biochemistry; Bacteria; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000514225,0.000431083,0.001028017,0.00005198762,0.0002253132,0.0001894322,0.001032956,0.0005576369,0.0006543265],"category_scores_gemma":[0.00002453335,0.0001227511,0.0006026127,0.0007027556,0.00009988961,0.00005751827,0.0004540338,0.0008113025,0.000501056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001790439,"about_ca_system_score_gemma":0.00007465693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000113422,"about_ca_topic_score_gemma":0.00009479876,"domain_scores_codex":[0.9975293,0.0003645387,0.0004978346,0.0006551569,0.0002501933,0.000702996],"domain_scores_gemma":[0.9989917,0.0005161238,0.0001902014,0.0001680189,0.00002918711,0.0001048028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001435064,0.0001390339,0.000003122794,0.002028997,0.00003430302,0.00001900982,0.00004463559,2.54257e-7,0.8299278,0.0001686764,0.007474354,0.1601455],"study_design_scores_gemma":[0.0001498154,0.00003377729,0.00001532304,0.00153396,0.0001514307,0.00003863788,0.000120194,9.615652e-7,0.002375627,0.0001771347,0.9949775,0.0004256929],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009131134,0.9965013,0.000008432723,0.0001349082,0.0004090029,0.0009636077,0.0001361323,0.00003372017,0.0008997417],"genre_scores_gemma":[0.002738843,0.9951634,0.00005099102,0.0000753941,0.0004692537,0.00002654671,0.000292606,0.00000659025,0.001176376],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9875031,"threshold_uncertainty_score":0.7164416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09857328609706657,"score_gpt":0.2956345524689956,"score_spread":0.197061266371929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}