{"id":"W2979098105","doi":"","title":"Structural and Functional Characterization of IclR Transcription Regulators","year":2009,"lang":"en","type":"dissertation","venue":"Library and Archives Canada (Government of Canada)","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Argonne National Laboratory; Canadian Institutes of Health Research; National Institutes of Health; University of Toronto","keywords":"Effector; Regulator; Isothermal titration calorimetry; Biology; Transcription factor; Computational biology; Cell biology; Biochemistry; Chemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002597121,0.0002136951,0.0002266471,0.0002227477,0.0001816256,0.0002633834,0.0003384891,0.0001933648,0.0008135868],"category_scores_gemma":[0.0003394922,0.00009367521,0.0002353332,0.0002154318,0.0001874723,0.0001658756,0.0001237532,0.0004565737,0.000331248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005265185,"about_ca_system_score_gemma":0.0002823774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001915748,"about_ca_topic_score_gemma":0.00144405,"domain_scores_codex":[0.9998226,0.0000243114,0.0000117931,0.00003609959,0.00007433323,0.00003089694],"domain_scores_gemma":[0.9998054,0.00003835488,0.00004098163,0.00002542987,0.00004563541,0.00004414434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004376619,0.00001481766,0.0002863292,0.00001831886,0.000001313512,0.0000255295,0.00002159107,0.0001907115,0.9981687,0.0000865615,0.00002793793,0.001114285],"study_design_scores_gemma":[0.000008704281,0.0001243389,0.005386949,0.000004695066,0.000006612522,0.0001824994,0.00005371779,0.001922194,0.9883881,0.00004423351,0.003871805,0.000006150372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990081,0.001245813,0.005914448,0.0001526982,0.00001525744,0.00003341098,0.0006399569,0.00008171763,0.001835696],"genre_scores_gemma":[0.9843084,0.0006923268,0.009103363,0.00010183,0.00001200702,0.00003797696,0.003170634,0.00005418615,0.002519294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001915748,"threshold_uncertainty_score":0.003820181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002805033002368262,"score_gpt":0.1595755401186977,"score_spread":0.1567705071163294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}