{"id":"W2979223628","doi":"10.2210/pdb4h5f/pdb","title":"Crystal structure of an amino acid ABC transporter substrate-binding protein from Streptococcus pneumoniae Canada MDR_19A bound to L-arginine, form 1","year":2012,"lang":"en","type":"paratext","venue":"","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"ATP-binding cassette transporter; Streptococcus pneumoniae; Arginine; Transporter; Amino acid; Chemistry; Plasma protein binding; Transport protein; Biochemistry; Microbiology; Biology; Gene; Antibiotics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000143428,0.0003890045,0.0007600427,0.0002142186,0.0007382987,0.0006003847,0.000868455,0.0006838627,0.003537718],"category_scores_gemma":[0.0004620719,0.0002349483,0.0002286965,0.0005583073,0.0002083923,0.0002182417,0.0002205912,0.001157198,0.0005811097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002335457,"about_ca_system_score_gemma":0.001889824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.07059053,"about_ca_topic_score_gemma":0.08987133,"domain_scores_codex":[0.9998367,0.00001172454,0.000006494836,0.00001869633,0.00008959502,0.00003679898],"domain_scores_gemma":[0.9998666,0.00003290299,0.0000227534,0.000003874382,0.00003854949,0.00003534092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005166584,0.001647855,0.02661258,0.002058132,0.0005382493,0.0160911,0.001318076,0.01526091,0.7789824,0.007300571,0.1055003,0.03952326],"study_design_scores_gemma":[0.00309312,0.001912424,0.2815683,0.000479555,0.0007272557,0.01096442,0.003229455,0.1047223,0.2835408,0.002238478,0.3071272,0.0003965987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9694904,0.006672273,0.0009797389,0.002270206,0.0003556044,0.00006146156,0.006762723,0.0002291159,0.01317849],"genre_scores_gemma":[0.9522334,0.004564915,0.004480179,0.0005670495,0.00007115403,0.00005208829,0.02260653,0.00008216549,0.01534241],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.07059053,"threshold_uncertainty_score":0.1403593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009982938140937654,"score_gpt":0.2333862934055627,"score_spread":0.223403355264625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}