{"id":"W2979267705","doi":"","title":"Microfluidic system for pulsed stimulation and time course analysis of mammalian cells: Identification of the minimal TNF-alpha pulse duration for NF-KAPPAB activation in HeLa cells","year":2012,"lang":"en","type":"article","venue":"","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Stimulation; HeLa; Tumor necrosis factor alpha; Pulse (music); Cell biology; Microfluidics; Chemistry; Biology; Immunology; Cell culture; Materials science; Engineering; Nanotechnology; Electrical engineering; Neuroscience; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002866764,0.0003084327,0.0004415317,0.0002428174,0.0002748532,0.0004203426,0.0003559678,0.000301765,0.0009068733],"category_scores_gemma":[0.0003399842,0.0002363518,0.0002295117,0.0002116358,0.0001827386,0.0002294529,0.0002012475,0.000471297,0.000268617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006945246,"about_ca_system_score_gemma":0.0004963519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005401621,"about_ca_topic_score_gemma":0.001022676,"domain_scores_codex":[0.999813,0.00001681453,0.00001737689,0.00006218941,0.00005248894,0.00003819948],"domain_scores_gemma":[0.9998263,0.00007414107,0.00003328683,0.00001396974,0.0000283291,0.00002408087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003862949,0.000009996378,0.00007276505,0.00002185997,0.000001954725,0.000008797853,0.0000104093,0.00005360853,0.9986038,0.0000922845,0.00004083256,0.001045087],"study_design_scores_gemma":[0.000009101949,0.00007364123,0.001135231,0.000004348719,0.00000823993,0.00003985993,0.00001103388,0.002214525,0.9951836,0.00005712123,0.001255365,0.000007860256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7783467,0.00349813,0.2120594,0.0004864104,0.0003914465,0.0002400086,0.001660681,0.0008375554,0.002479585],"genre_scores_gemma":[0.8515427,0.001800203,0.1423027,0.0002391095,0.0001090256,0.0008359618,0.0009035167,0.0001013312,0.002165572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009068733,"threshold_uncertainty_score":0.005039155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008864840078851735,"score_gpt":0.2605507153235851,"score_spread":0.2516858752447334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}