{"id":"W2979298689","doi":"10.1038/s41564-019-0580-9","title":"BioID screen of Salmonella type 3 secreted effectors reveals host factors involved in vacuole positioning and stability during infection","year":2019,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; University of Toronto; University Health Network; Princess Margaret Cancer Centre; Hospital for Sick Children; University of Ottawa","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Effector; Vacuole; Salmonella; Host (biology); Microbiology; Biology; Cell biology; Bacteria; Genetics; Cytoplasm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001624377,0.0003361076,0.0003524171,0.0003463441,0.0002604803,0.0004026871,0.00024138,0.0002752345,0.001457029],"category_scores_gemma":[0.0002034896,0.0001860169,0.0003421549,0.0002893161,0.0001881859,0.0001653241,0.0003030222,0.0003971523,0.0007361149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004460451,"about_ca_system_score_gemma":0.0002267323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001507975,"about_ca_topic_score_gemma":0.002724856,"domain_scores_codex":[0.9998302,0.00002459478,0.00001447035,0.00002993021,0.0000554029,0.0000452995],"domain_scores_gemma":[0.9998479,0.00004894273,0.00002099924,0.00001679651,0.00002792782,0.00003745044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001213196,0.000009788088,0.0003168416,0.000008812527,0.000001679426,0.00002956488,0.000008249018,0.00002470698,0.9990739,0.00001857623,0.00001425811,0.0003723363],"study_design_scores_gemma":[0.000005889827,0.0001346583,0.009469174,0.00000174066,0.000007925213,0.0001742558,0.00006347918,0.0004593552,0.9890429,0.00001668488,0.0006202029,0.000003776661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948396,0.0004657592,0.002573338,0.0000866398,0.00001252878,0.00002236804,0.0009655629,0.00005108522,0.0009831021],"genre_scores_gemma":[0.9880117,0.0002701819,0.003990177,0.00008965252,0.000004223106,0.00002919949,0.002841904,0.00004016305,0.004722784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001507975,"threshold_uncertainty_score":0.004874289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00379753114721227,"score_gpt":0.2170203081099189,"score_spread":0.2132227769627066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}