{"id":"W2979357550","doi":"10.1016/j.cjca.2019.07.178","title":"CO-DELIVERY OF MICRORNA-126 ENHANCES VASCULAR ENDOTHELIAL GROWTH FACTOR A ANGIOGENIC TREATMENT IN DIABETIC ISCHEMIA VIA ACTIVATION OF AKT/ENOS SIGNALING","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Medicine; Vascular endothelial growth factor; Angiogenesis; Protein kinase B; Enos; Matrigel; Vascular permeability; Vascular endothelial growth factor A; Cancer research; Ischemia; Neovascularization; Endocrinology; Internal medicine; Signal transduction; Cell biology; Nitric oxide; Biology; Nitric oxide synthase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003767641,0.0004065399,0.0006878397,0.0002674374,0.0002453304,0.0004694779,0.0002824251,0.0006091105,0.001811104],"category_scores_gemma":[0.0003070658,0.0002494931,0.0004819809,0.0002050781,0.0003860997,0.0004041519,0.0002417274,0.00112293,0.0004510459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003764126,"about_ca_system_score_gemma":0.0005433541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007238284,"about_ca_topic_score_gemma":0.001056053,"domain_scores_codex":[0.9995613,0.00005707289,0.00004419455,0.0001137644,0.0001201784,0.0001034551],"domain_scores_gemma":[0.9998889,0.00002090343,0.0000262638,0.000009437914,0.00001683925,0.00003774319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002290598,0.0004297944,0.0002739124,0.0001754813,0.00004209506,0.000105657,0.00003985879,0.0003284812,0.9879496,0.0005690654,0.0005345379,0.007261024],"study_design_scores_gemma":[0.0004068546,0.002390641,0.002481809,0.00001314704,0.0001630135,0.0002947356,0.00005141783,0.005657237,0.9828182,0.0001717814,0.005521194,0.00002985927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867502,0.002718818,0.004692427,0.0003199809,0.0006687368,0.000116254,0.0002820369,0.0002175852,0.004233917],"genre_scores_gemma":[0.9928513,0.0007285711,0.00325746,0.0001519279,0.00005186417,0.0001163786,0.0002074721,0.00002279869,0.002612432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001811104,"threshold_uncertainty_score":0.006058812,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008479382975574752,"score_gpt":0.2208018150835733,"score_spread":0.2123224321079986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}