{"id":"W2979373204","doi":"10.1182/blood.v104.11.3842.3842","title":"Identifying Mechanisms of Enhanced NK Cell Cytotoxicity Using Permanent NK Cell Lines.","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Toronto General Hospital; Canadian Blood Services; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Cytotoxicity; NKG2D; CD16; Natural killer cell; Lymphokine-activated killer cell; Biology; Cell culture; Flow cytometry; Cytotoxic T cell; Antibody-dependent cell-mediated cytotoxicity; Perforin; Receptor; Cell biology; Interleukin 21; Molecular biology; Immunology; CD8; CD3; Antigen; In vitro; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004875691,0.0004162591,0.0004306283,0.0001972003,0.00009457555,0.0004166561,0.000373784,0.0003397606,0.00165918],"category_scores_gemma":[0.0003702838,0.0001243677,0.0002535934,0.0001711275,0.0003448538,0.0003637206,0.0004295212,0.0006841743,0.0005627365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001935611,"about_ca_system_score_gemma":0.0001364363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001615204,"about_ca_topic_score_gemma":0.0002051146,"domain_scores_codex":[0.9995403,0.0001075018,0.0000730355,0.00009330503,0.000134229,0.00005157788],"domain_scores_gemma":[0.999517,0.0001537899,0.00009980717,0.0001469958,0.00005444467,0.00002794783],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001443726,0.0000342149,0.0005335503,0.0000950879,0.000007838762,0.00004533715,0.00001531953,0.0001083613,0.9961898,0.0001214278,0.00003481215,0.002669856],"study_design_scores_gemma":[0.0000275549,0.0008761982,0.003053053,0.000009359654,0.0000251537,0.0004957198,0.00002280413,0.0009520112,0.9929481,0.00007070985,0.001515407,0.000003904845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9708134,0.00377841,0.02270699,0.0001016857,0.00007823792,0.0001700866,0.0007441663,0.0001832488,0.001423833],"genre_scores_gemma":[0.9891407,0.0007941501,0.00717225,0.00004740999,0.00002088943,0.0001382791,0.0008380077,0.00002281422,0.001825442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00165918,"threshold_uncertainty_score":0.005550504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01700879189493418,"score_gpt":0.239719240505113,"score_spread":0.2227104486101788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}