{"id":"W2979393303","doi":"10.1182/blood.v108.11.2942.2942","title":"Determination of a Limited Sampling Strategy for IV Busulfan Dose Individualization in Children.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Busulfan; Area under the curve; Medicine; Intraclass correlation; Coefficient of variation; Pharmacokinetics; Urology; Internal medicine; Gastroenterology; Hematopoietic stem cell transplantation; Chemistry; Transplantation; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004388993,0.0003626718,0.0005299965,0.0005083869,0.000203162,0.0005077658,0.0003456797,0.0002398359,0.0003707344],"category_scores_gemma":[0.01392065,0.0002494481,0.0003312057,0.0005077479,0.0002972653,0.0004446312,0.0003172434,0.0003902066,0.0001780296],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007356044,"about_ca_system_score_gemma":0.0009874668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0024824,"about_ca_topic_score_gemma":0.002658122,"domain_scores_codex":[0.9971892,0.001433352,0.0003272246,0.0003477461,0.000589218,0.0001131278],"domain_scores_gemma":[0.9948452,0.001880952,0.002000927,0.0004085396,0.0006673436,0.0001970545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001194818,0.00006661136,0.9305241,0.000121632,0.00006909094,0.0002274766,0.0003149363,0.003132398,0.008771234,0.0001557138,0.0005196974,0.05490226],"study_design_scores_gemma":[0.0001058393,0.004964439,0.9122907,0.0001462191,0.0002332739,0.002489345,0.0005246108,0.03694899,0.03804571,0.0002845453,0.003925408,0.0000408885],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832412,0.001139463,0.01430066,0.0001042885,0.00001849899,0.0001549882,0.0002443237,0.00009873114,0.0006977199],"genre_scores_gemma":[0.9843904,0.0002302626,0.01488904,0.00004081365,0.000009304792,0.0001244204,0.0001941792,0.00001832243,0.0001032397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004388993,"threshold_uncertainty_score":0.02321148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2648427197199653,"score_gpt":0.400707476426206,"score_spread":0.1358647567062407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}