{"id":"W2979400106","doi":"10.14309/01.ajg.0000593520.44985.d3","title":"996 Disease Characteristics of Acute Hepatic Porphyria Patients: ENVISION, a Phase 3 Global, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial","year":2019,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Porphyrin Metabolism and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; Alberta Hospital Edmonton","funders":"","keywords":"Medicine; Internal medicine; Kidney disease; Placebo; Population; Chronic liver disease; Liver disease; Adverse effect; Multicenter trial; Randomized controlled trial; Gastroenterology; Surgery; Cirrhosis; Pathology; Multicenter study","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001938137,0.001647381,0.00264284,0.0004935106,0.0004935979,0.001449098,0.0007209741,0.001971407,0.007517672],"category_scores_gemma":[0.001368465,0.0006037704,0.001529656,0.0004376065,0.001015931,0.00108554,0.0003805317,0.002294861,0.0009790144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004807855,"about_ca_system_score_gemma":0.0008882217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004037586,"about_ca_topic_score_gemma":0.001032824,"domain_scores_codex":[0.9994531,0.0002788084,0.00003862557,0.0001116571,0.00004266439,0.00007516058],"domain_scores_gemma":[0.9992672,0.0002134734,0.0002174026,0.00004684927,0.00005433744,0.0002007701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9756979,0.005023499,0.001348904,0.001021726,0.0007919482,0.00004899421,0.000056152,0.0002399762,0.002076931,0.0001453909,0.001160039,0.01238832],"study_design_scores_gemma":[0.9695618,0.02743043,0.001604275,0.00005003428,0.0003046809,0.00003594021,0.00001691619,0.0002074026,0.0001465207,0.00008894135,0.0005426761,0.00001037748],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759628,0.01070884,0.0008707773,0.001249608,0.0005453016,0.004900879,0.001810605,0.0002142678,0.003736938],"genre_scores_gemma":[0.9837189,0.003530039,0.002049919,0.001768111,0.0006004008,0.005008076,0.001291881,0.00002742589,0.002005161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007517672,"threshold_uncertainty_score":0.02514911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005157401253019397,"score_gpt":0.2663758276265353,"score_spread":0.2612184263735159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}