{"id":"W2979433645","doi":"10.1182/blood.v116.21.122.122","title":"Iron Overload Accelerates Development of Leukaemia: Evidence From a Mouse Model","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Bone marrow; Haematopoiesis; Context (archaeology); Ferritin; DNA damage; Biology; Cancer research; Chemistry; Internal medicine; Medicine; Stem cell; Immunology; Biochemistry; Genetics; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009683002,0.001170577,0.0006328099,0.002212898,0.0003369846,0.0005455253,0.0006754043,0.001023279,0.003014587],"category_scores_gemma":[0.0002773762,0.000394319,0.0007190833,0.0004986321,0.0005874903,0.0005757092,0.0004713251,0.00138855,0.000991495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004227079,"about_ca_system_score_gemma":0.0002102372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004572061,"about_ca_topic_score_gemma":0.0005684475,"domain_scores_codex":[0.9995508,0.0001288985,0.00004761098,0.0000855261,0.0001288501,0.00005837815],"domain_scores_gemma":[0.9995689,0.00007773239,0.0001398221,0.00006949,0.00004822773,0.00009582516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001977575,0.001060423,0.002173795,0.0002971089,0.00006414374,0.0004530984,0.0001211454,0.000170357,0.9867615,0.0004577065,0.0004572425,0.006005917],"study_design_scores_gemma":[0.0008006066,0.01845706,0.02544222,0.0001977512,0.0004057325,0.00535305,0.0001700611,0.002753469,0.9264148,0.0008057412,0.0191393,0.0000602426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9753032,0.007289269,0.009441024,0.0007529962,0.00009643146,0.0003155898,0.001554869,0.0005941426,0.004652638],"genre_scores_gemma":[0.9749229,0.007269168,0.006001097,0.0003414765,0.00007738132,0.0003847626,0.001830421,0.00009259583,0.009080271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003014587,"threshold_uncertainty_score":0.01008481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02055707004373822,"score_gpt":0.2551512502150471,"score_spread":0.2345941801713089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}