{"id":"W2979496671","doi":"10.1182/blood.v116.21.2403.2403","title":"High-Dose Melphalan for AL Amyloidosis: The Importance of Case Selection to Improve Clinical Outcomes","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Princess Margaret Cancer Centre","funders":"","keywords":"Melphalan; AL amyloidosis; Medicine; Internal medicine; Multiple myeloma; Autologous stem-cell transplantation; Regimen; Amyloidosis; Hematopoietic stem cell transplantation; Surgery; Oncology; Transplantation; Gastroenterology; Immunology; Immunoglobulin light chain; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001186704,0.0001231088,0.0003518696,0.0005785539,0.0002902035,0.0004849445,0.0002262738,0.000216485,0.0006965994],"category_scores_gemma":[0.003245669,0.00007694905,0.0002043395,0.0005272799,0.0001859967,0.0004862348,0.0003190259,0.0002506528,0.000124603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002004553,"about_ca_system_score_gemma":0.0002246431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002355545,"about_ca_topic_score_gemma":0.0004820091,"domain_scores_codex":[0.999391,0.0003132312,0.00009724589,0.00005881651,0.00009052954,0.00004924776],"domain_scores_gemma":[0.9983304,0.0006866788,0.0005236519,0.00009029524,0.0001101784,0.000258801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001354891,0.0002327015,0.9461755,0.00005285186,0.00005046278,0.002640509,0.0001303476,0.0002616263,0.001630118,0.00009560858,0.0006002847,0.04677512],"study_design_scores_gemma":[0.0001812716,0.002009303,0.9715144,0.00009323041,0.00009081626,0.0175399,0.0005139969,0.003936355,0.001702762,0.0004811828,0.001915133,0.00002170466],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966674,0.001456762,0.0005815447,0.0002089157,0.00002148499,0.00006205007,0.00006455128,0.000008700479,0.0009284912],"genre_scores_gemma":[0.9991164,0.0002346624,0.0004345471,0.00004230907,0.00004095592,0.00001920813,0.0000676277,0.000001607216,0.00004270455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001186704,"threshold_uncertainty_score":0.006275952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01400405650429452,"score_gpt":0.3186089048867387,"score_spread":0.3046048483824442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}