{"id":"W2979510277","doi":"10.1182/blood.v128.22.1226.1226","title":"Donor Lymphocytes Depleted of Alloreactive T-Cells (ATIR101) Improve Event-Free Survival (GRFS) and Overall Survival in a T-Cell Depleted Haploidentical HSCT: Phase 2 Trial in Patients with AML and ALL","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Juravinski Hospital; Université de Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"ThioTEPA; Fludarabine; Medicine; Hematopoietic stem cell transplantation; CD34; Graft-versus-host disease; Internal medicine; Melphalan; Total body irradiation; Gastroenterology; Stem cell; Donor lymphocyte infusion; Transplantation; Phases of clinical research; Immunology; Surgery; Clinical trial; Cyclophosphamide; Chemotherapy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001118026,0.001145441,0.001220726,0.0003430746,0.0003089595,0.0007934913,0.000673376,0.0006675588,0.002142181],"category_scores_gemma":[0.0003689829,0.0003650016,0.000649224,0.0002423962,0.000581559,0.0004650563,0.0003344176,0.002247981,0.0003877741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004686663,"about_ca_system_score_gemma":0.0008206822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003361167,"about_ca_topic_score_gemma":0.0008783537,"domain_scores_codex":[0.9997064,0.0001614351,0.00001661547,0.00004029533,0.00002400265,0.00005123335],"domain_scores_gemma":[0.9996742,0.0000484775,0.00006426703,0.00002988518,0.00001371159,0.0001695208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6592286,0.07743987,0.01182299,0.0008365874,0.001249989,0.0004619136,0.0003614564,0.003673672,0.0871112,0.0005243487,0.00373831,0.1535511],"study_design_scores_gemma":[0.4228198,0.5492108,0.0134613,0.00004645151,0.0004915221,0.0004605573,0.00007378676,0.001520469,0.009397631,0.0001804158,0.002302307,0.00003491921],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977199,0.0008579022,0.0001835028,0.0001393794,0.000042638,0.000368633,0.0001761316,0.00003651329,0.000475388],"genre_scores_gemma":[0.9964017,0.0006821156,0.0004805253,0.0002622471,0.00009563776,0.0006043878,0.0006406005,0.000008927166,0.0008238257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002142181,"threshold_uncertainty_score":0.007166326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01072469247725687,"score_gpt":0.2426826855259805,"score_spread":0.2319579930487236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}