{"id":"W2979548369","doi":"10.1016/s1470-2045(19)30493-0","title":"Patient-reported quality of life after tisagenlecleucel infusion in children and young adults with relapsed or refractory B-cell acute lymphoblastic leukaemia: a global, single-arm, phase 2 trial","year":2019,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Cancer Institute; Novartis","keywords":"Medicine; Refractory (planetary science); Quality of life (healthcare); Young adult; Pediatrics; Oncology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008857269,0.0002185642,0.00101316,0.00009514124,0.00003358359,0.00001197481,0.0001568506,0.0002638469,0.0007637141],"category_scores_gemma":[0.0003032808,0.0001314766,0.0000697221,0.0003643542,0.0002197636,0.00007167063,0.0001402509,0.0004302223,0.00001679451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004711486,"about_ca_system_score_gemma":0.0007665189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007913811,"about_ca_topic_score_gemma":0.0006716986,"domain_scores_codex":[0.9973854,0.0005882599,0.0006992227,0.000422854,0.0004574904,0.0004467332],"domain_scores_gemma":[0.9982268,0.0003750288,0.000436516,0.0006739114,0.0001314335,0.0001562797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8169523,0.003942167,0.1145714,0.0001376337,0.0003172821,0.0001949799,0.001528838,0.000002530738,0.04745417,0.000005431292,0.0004632701,0.01443],"study_design_scores_gemma":[0.6494795,0.06680353,0.2782211,0.0003159372,0.0003405786,0.0005649751,0.0004560057,0.0001431578,0.00178032,0.00004358747,0.001467045,0.0003842732],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949364,0.0002753133,0.00000710516,0.0003255189,0.0001995259,0.002289014,0.00005417752,0.00003717018,0.001875782],"genre_scores_gemma":[0.9981363,0.0002736223,0.0001490452,0.0005904725,0.0002000637,0.00008341647,0.00005001191,0.00002762789,0.0004894584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1674728,"threshold_uncertainty_score":0.8362134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03486376564826552,"score_gpt":0.345367385747986,"score_spread":0.3105036200997205,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}