{"id":"W2979563030","doi":"10.1016/j.tem.2019.08.009","title":"The Complexity of Making Ubiquinone","year":2019,"lang":"en","type":"review","venue":"Trends in Endocrinology and Metabolism","topic":"Coenzyme Q10 studies and effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Mitochondrion; Reactive oxygen species; Coenzyme Q – cytochrome c reductase; Biology; Mitochondrial respiratory chain; Mitochondrial disease; Inner mitochondrial membrane; Biochemistry; Respiratory chain; Antioxidant; Electron transport chain; Cell biology; Mitochondrial DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001611574,0.0002952449,0.001123272,0.0001372847,0.000094237,0.000007942662,0.0002769261,0.0002198705,0.00001078276],"category_scores_gemma":[0.00004499163,0.0001933434,0.0002535408,0.0001648539,0.000606099,0.000001539497,0.0004476007,0.0002764496,0.000004476153],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006614267,"about_ca_system_score_gemma":0.00003752244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001968582,"about_ca_topic_score_gemma":0.000141803,"domain_scores_codex":[0.9985009,0.0002276962,0.0004015184,0.0003861648,0.00006814425,0.0004155895],"domain_scores_gemma":[0.9991807,0.00007494223,0.0002286288,0.0004661994,0.00002432352,0.00002516476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002311531,0.00002528074,0.00001518197,0.0008787315,0.0002263353,0.000005650209,0.00001982161,3.291366e-7,0.00001953441,0.007698702,0.002659665,0.9884276],"study_design_scores_gemma":[0.0003258639,0.00005532561,0.0004169081,0.0002724037,0.000266204,0.00006938076,0.00001551764,7.59191e-7,0.00003396564,0.00007668119,0.9982892,0.00017778],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000267112,0.9974418,0.000003932957,0.00006326522,0.000563306,0.00016985,0.00003378073,0.000005411706,0.00145149],"genre_scores_gemma":[0.002357151,0.9961354,0.00005903573,0.00002866438,0.0002105896,0.00005147987,0.0000604073,0.00002226566,0.001075064],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9956295,"threshold_uncertainty_score":0.7884315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0861755277527412,"score_gpt":0.3681543005595554,"score_spread":0.2819787728068143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}