{"id":"W2979563030","doi":"10.1016/j.tem.2019.08.009","title":"The Complexity of Making Ubiquinone","year":2019,"lang":"en","type":"review","venue":"Trends in Endocrinology and Metabolism","topic":"Coenzyme Q10 studies and effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Mitochondrion; Reactive oxygen species; Coenzyme Q – cytochrome c reductase; Biology; Mitochondrial respiratory chain; Mitochondrial disease; Inner mitochondrial membrane; Biochemistry; Respiratory chain; Antioxidant; Electron transport chain; Cell biology; Mitochondrial DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001003905,0.0009606613,0.001071812,0.00077028,0.000323274,0.001587474,0.001125673,0.00138842,0.002308282],"category_scores_gemma":[0.0007855196,0.0003083804,0.0002636339,0.001014001,0.00163295,0.00302918,0.001363749,0.002574703,0.001509077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009124502,"about_ca_system_score_gemma":0.0009942908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007957371,"about_ca_topic_score_gemma":0.001351654,"domain_scores_codex":[0.9997905,0.00003840079,0.00002463437,0.00004881398,0.00006925238,0.00002837113],"domain_scores_gemma":[0.9997277,0.0001433195,0.00002345167,0.00001622671,0.0000575459,0.00003170905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001484878,0.00004009226,0.000167892,0.01163602,0.00005949204,0.000325982,0.0001479398,0.0005857425,0.01133393,0.03584148,0.02521557,0.9144974],"study_design_scores_gemma":[0.00001491518,0.0000564657,0.0002977991,0.0009143184,0.00002942786,0.000454924,0.00008522628,0.00008456159,0.001782108,0.01691355,0.9793503,0.00001643511],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001770573,0.9969605,0.0004175726,0.000956918,0.0005810563,0.000001489149,0.00001089592,0.00000742411,0.0008870565],"genre_scores_gemma":[0.001498858,0.9966467,0.0002874178,0.0003715111,0.0003746378,0.000003782704,0.00001641711,0.000002304141,0.0007983455],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002308282,"threshold_uncertainty_score":0.007721961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0861755277527412,"score_gpt":0.3681543005595554,"score_spread":0.2819787728068143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}