{"id":"W2979606780","doi":"10.1016/s2468-1253(19)30320-6","title":"Safety of two different doses of simvastatin plus rifaximin in decompensated cirrhosis (LIVERHOPE-SAFETY): a randomised, double-blind, placebo-controlled, phase 2 trial","year":2019,"lang":"en","type":"article","venue":"The Lancet. Gastroenterology & hepatology","topic":"Liver Disease and Transplantation","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Horizon 2020 Framework Programme; Grifols; Intercept Pharmaceuticals; Gilead Sciences; Horizon 2020; Instituto de Salud Carlos III; Spanish Clinical Research Network; Pfizer","keywords":"Rifaximin; Medicine; Simvastatin; Placebo; Double blind; Cirrhosis; Internal medicine; Gastroenterology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001805789,0.002624288,0.004055004,0.0005615152,0.0005065285,0.00125325,0.001149832,0.003763829,0.01018528],"category_scores_gemma":[0.002299292,0.001028382,0.002596716,0.0004146678,0.001511179,0.001612503,0.0006170257,0.003537456,0.001696389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008890574,"about_ca_system_score_gemma":0.0008856441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007501295,"about_ca_topic_score_gemma":0.001307995,"domain_scores_codex":[0.9991475,0.0004074024,0.00005689567,0.0001895517,0.00005463609,0.0001439008],"domain_scores_gemma":[0.999104,0.0002960871,0.0001930017,0.00008816908,0.00006104132,0.0002577158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9909209,0.001916948,0.0001716988,0.000489538,0.0005977259,0.00002533975,0.00003161258,0.00007630765,0.001150266,0.00005343338,0.0003522761,0.00421396],"study_design_scores_gemma":[0.9818555,0.01713619,0.0004265992,0.00001552253,0.000182035,0.00001174435,0.0000100406,0.00005562173,0.0001070998,0.00004975041,0.0001433564,0.000006611423],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812981,0.00749598,0.0007988573,0.001584176,0.001233194,0.00349867,0.00158672,0.0002058302,0.002298522],"genre_scores_gemma":[0.9812704,0.003360396,0.001879604,0.002043837,0.001026353,0.004894325,0.001528136,0.00003551594,0.003961353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01018528,"threshold_uncertainty_score":0.03407311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02888913664553694,"score_gpt":0.311672063742598,"score_spread":0.2827829270970611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}