{"id":"W2979625562","doi":"10.1182/blood.v120.21.3925.3925","title":"Updated Interim Results of the Safety and Efficacy of Different Lenalidomide Starting Dose Regimens in Patients with Relapsed or Refractory (rel/ref) Chronic Lymphocytic Leukemia (CLL) (CC-5013-CLL-009 Study)","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre","funders":"","keywords":"Bendamustine; Medicine; Tolerability; Lenalidomide; Regimen; Internal medicine; Chronic lymphocytic leukemia; Tumor lysis syndrome; Rituximab; Neutropenia; Phases of clinical research; Febrile neutropenia; Interim analysis; Clinical trial; Oncology; Pharmacology; Adverse effect; Leukemia; Chemotherapy; Lymphoma; Multiple myeloma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009052505,0.0003826175,0.0008984405,0.0002317785,0.00008722933,0.00001413988,0.0003318722,0.0001735082,0.00002272131],"category_scores_gemma":[0.0009891781,0.0002180211,0.0001010737,0.0005923275,0.0002852273,0.000167653,0.0004083411,0.0004651094,0.000006011582],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.01949872,"about_ca_system_score_gemma":0.007227304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001169995,"about_ca_topic_score_gemma":0.0004321455,"domain_scores_codex":[0.9960523,0.000418449,0.001266611,0.0005191729,0.0009841751,0.000759288],"domain_scores_gemma":[0.9970831,0.0005634955,0.0006510011,0.001224058,0.0002172502,0.0002611227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2994817,0.07826731,0.5395533,0.004025686,0.005306574,0.0003838936,0.03530859,0.0003900396,0.02132782,0.0001494167,0.001232977,0.01457268],"study_design_scores_gemma":[0.4815946,0.004202343,0.4947162,0.001447761,0.0005783886,0.0000270593,0.0005642477,0.0004652732,0.01595318,0.000002904187,0.0001560063,0.0002920881],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997021,0.000451146,0.000001520518,0.00003912034,0.0001032374,0.002042532,0.00003042646,0.00005089043,0.0002601873],"genre_scores_gemma":[0.999263,0.0000903887,0.00005518298,0.00003795723,0.00008931262,0.00002660247,0.00004043622,0.00008138116,0.0003157284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1821129,"threshold_uncertainty_score":0.9984008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01843605526415957,"score_gpt":0.2763225775722773,"score_spread":0.2578865223081177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}